Hosseinidoust Zeinab, Olsson Adam L J, Tufenkji Nathalie
Department of Chemical Engineering, McGill University, Montreal, QC, Canada H3A 0C5.
Department of Chemical Engineering, McGill University, Montreal, QC, Canada H3A 0C5.
Colloids Surf B Biointerfaces. 2014 Dec 1;124:2-16. doi: 10.1016/j.colsurfb.2014.05.036. Epub 2014 Jun 2.
Bacteriophage-functionalized bioactive surfaces are functional materials that can be used as antimicrobial surfaces in medical applications (e.g., indwelling medical devices or wound dressings) or as biosensors for bacterial capture and detection. Despite offering immense potential, designing efficient phage-functionalized bioactive surfaces is hampered by a number of challenges. This review offers an overview of the current state of knowledge in this field and presents a critical perspective of the technological promises and challenges.
噬菌体功能化生物活性表面是一种功能材料，可在医学应用中用作抗菌表面（例如植入式医疗设备或伤口敷料），或用作细菌捕获和检测的生物传感器。尽管具有巨大潜力，但设计高效的噬菌体功能化生物活性表面面临诸多挑战。本文综述了该领域的当前知识状态，并对技术前景和挑战提出了批判性观点。
