Xu Meiyun, Kinoshita Yusuke, Tamiaki Hitoshi
Graduate School of Life Sciences, Ritsumeikan University, Kusatsu, Shiga 525-8577, Japan.
Graduate School of Life Sciences, Ritsumeikan University, Kusatsu, Shiga 525-8577, Japan.
Bioorg Med Chem Lett. 2014 Aug 15;24(16):3997-4000. doi: 10.1016/j.bmcl.2014.06.022. Epub 2014 Jun 18.
A methyl group at the 2-position of methyl mesopyropheophorbide-a was transformed to the 2-formyl group to give methyl mesopyropheophorbide-f, one of the chlorophyll-f analogs. The 2-formylation moved the redmost electronic absorption band in a solution to a longer wavelength and the bathochromic shift was comparable to that by the 3-formylation. Zinc complex of the synthetic compound in solutions showed similar visible absorption spectra as those of naturally occurring chlorophyll-f.
将甲基中焦脱镁叶绿酸-a的2-位甲基转化为2-甲酰基，得到叶绿素-f类似物之一的甲基中焦脱镁叶绿酸-f。2-甲酰化使溶液中最红的电子吸收带移至更长波长，其红移与3-甲酰化引起的红移相当。该合成化合物在溶液中的锌配合物显示出与天然叶绿素-f相似的可见吸收光谱。
