揭开抗氧化剂的真相：线粒体应激反应解释了活性氧诱导的健康益处。 - Suppr

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超能文献

Unraveling the truth about antioxidants: mitohormesis explains ROS-induced health benefits.

作者信息

Ristow Michael

机构信息

Energy Metabolism Laboratory, ETH Zurich, Schwerzenbach-Zurich, Switzerland.

出版信息

Nat Med. 2014 Jul;20(7):709-11. doi: 10.1038/nm.3624.

DOI:10.1038/nm.3624

PMID:24999941

Abstract

摘要

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本文引用的文献

Metformin promotes lifespan through mitohormesis via the peroxiredoxin PRDX-2.二甲双胍通过过氧化物酶 PRDX-2 介导的 mitohormesis 促进寿命。

Proc Natl Acad Sci U S A. 2014 Jun 17;111(24):E2501-9. doi: 10.1073/pnas.1321776111. Epub 2014 Jun 2.

Sestrin2 inhibits uncoupling protein 1 expression through suppressing reactive oxygen species.硒蛋白2通过抑制活性氧来抑制解偶联蛋白1的表达。

Proc Natl Acad Sci U S A. 2014 May 27;111(21):7849-54. doi: 10.1073/pnas.1401787111. Epub 2014 May 13.

D-Glucosamine supplementation extends life span of nematodes and of ageing mice.补充D-葡萄糖胺可延长线虫和衰老小鼠的寿命。

Nat Commun. 2014 Apr 8;5:3563. doi: 10.1038/ncomms4563.

Mitohormesis.线粒体细胞自噬。

Cell Metab. 2014 May 6;19(5):757-66. doi: 10.1016/j.cmet.2014.01.011. Epub 2014 Feb 20.

Long-term multivitamin supplementation and cognitive function in men: a randomized trial.长期多种维生素补充与男性认知功能：一项随机试验。

Ann Intern Med. 2013 Dec 17;159(12):806-14. doi: 10.7326/0003-4819-159-12-201312170-00006.

Antioxidants accelerate lung cancer progression in mice.抗氧化剂加速小鼠肺癌进展。

Sci Transl Med. 2014 Jan 29;6(221):221ra15. doi: 10.1126/scitranslmed.3007653.

Muscle mitohormesis promotes longevity via systemic repression of insulin signaling.肌肉mitohormesis 通过全身抑制胰岛素信号传递促进长寿。

Cell. 2013 Oct 24;155(3):699-712. doi: 10.1016/j.cell.2013.09.021.

Antioxidant supplements and mortality.抗氧化补充剂与死亡率。

Curr Opin Clin Nutr Metab Care. 2014 Jan;17(1):40-4. doi: 10.1097/MCO.0000000000000009.

Vitamin and mineral supplements in the primary prevention of cardiovascular disease and cancer: An updated systematic evidence review for the U.S. Preventive Services Task Force.维生素和矿物质补充剂在心血管疾病和癌症一级预防中的作用：美国预防服务工作组的更新系统循证评价。

Ann Intern Med. 2013 Dec 17;159(12):824-34. doi: 10.7326/0003-4819-159-12-201312170-00729.

Screening for cognitive impairment in older adults: A systematic review for the U.S. Preventive Services Task Force.老年人认知障碍筛查：美国预防服务工作组的系统评价。

Ann Intern Med. 2013 Nov 5;159(9):601-12. doi: 10.7326/0003-4819-159-9-201311050-00730.

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