State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, Hubei Province, China; email:
Annu Rev Phytopathol. 2014;52:45-68. doi: 10.1146/annurev-phyto-102313-050222. Epub 2014 Jul 7.
Mycoviruses are viruses that infect fungi. A growing number of novel mycoviruses have expanded our knowledge of virology, particularly in taxonomy, ecology, and evolution. Recent progress in the study of mycoviruses has comprehensively improved our understanding of the properties of mycoviruses and has strengthened our confidence to explore hypovirulence-associated mycoviruses that control crop diseases. In this review, the advantages of using hypovirulence-associated mycoviruses to control crop diseases are discussed, and, as an example, the potential for Sclerotinia sclerotiorum hypovirulence-associated DNA virus 1 (SsHADV-1) to control the stem rot of rapeseed (Brassica napus) is also introduced. Fungal vegetative incompatibility is likely to be the key factor that limits the wide utilization of mycoviruses to control crop diseases; however, there are suggested strategies for resolving this problem.
真菌病毒是感染真菌的病毒。越来越多的新型真菌病毒拓展了我们对病毒学的认识，尤其是在分类学、生态学和进化方面。近年来，真菌病毒研究取得了进展，全面提高了我们对真菌病毒特性的认识，并增强了我们探索控制作物病害的弱毒相关真菌病毒的信心。在这篇综述中，讨论了利用弱毒相关真菌病毒控制作物病害的优势，并以 Sclerotinia sclerotiorum 弱毒相关 DNA 病毒 1（SsHADV-1）为例，介绍了其控制油菜（Brassica napus）茎腐病的潜力。真菌营养体不亲和性可能是限制真菌病毒广泛用于控制作物病害的关键因素，但已经提出了解决这一问题的策略。
