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颈部坏死性筋膜炎:6例报告并文献复习

Cervical necrotizing fasciitis: report of 6 cases and review of literature.

作者信息

Cruz Toro P, Callejo Castillo À, Tornero Saltó J, González Compta X, Farré A, Maños M

机构信息

Otorhinolaryngology Department, Hospital Universitari de Bellvitge, Feixa Llarga s/n, Hospitalet de Llobregat, 08907 Barcelona, Spain.

Otorhinolaryngology Department, Hospital Universitari de Bellvitge, Feixa Llarga s/n, Hospitalet de Llobregat, 08907 Barcelona, Spain.

出版信息

Eur Ann Otorhinolaryngol Head Neck Dis. 2014 Dec;131(6):357-359. doi: 10.1016/j.anorl.2013.08.006. Epub 2014 Jul 4.

Abstract

OBJECTIVE

Necrotizing fasciitis in the cervical region is a rare entity, characterized by a fulminant infection that causes extensive necrosis of the subcutaneous tissue and fascial planes, with high mortality and morbidity rates. The origin is generally odontogenic or pharyngeal, involving a mixed flora of microorganisms. Descending infection and mediastinal involvement are usually associated and are the main complications. The aim of the present study was to review the cases treated in our department and analyze diagnosis and treatment, supplementing the understanding of the disease.

METHODS

A retrospective study was performed on the clinical records of patients admitted to our center between January 2005 and June 2010 with diagnosis of necrotizing cervical fasciitis.

RESULTS

Six clinical records were reviewed. The origin of the infection was mainly oropharyngeal and odontogenic, with a mixed flora of Prevotella, Peptostreptococcus and coagulase-negative Staphylococcus. All patients presented mediastinal involvement: superior mediastinitis in 4 patients and superior and postero-inferior mediastinitis in 2 cases. All patients underwent early drainage by bilateral cervicotomy with mediastinal drainage by a cervical approach in those with superior mediastinal affection, and associated thoracotomy, in a single surgical step, for postero-inferior mediastinitis. Temporary tracheotomy was performed in all cases. All received broad spectrum antibiotics, with a medium hospital stay of 37 days. There were no deaths reported.

CONCLUSION

Concerning cervical necrotizing fasciitis, early diagnosis and surgical treatment associated to antibiotics and intensive medical care are essential to obtain a favorable outcome.

摘要

目的

颈部坏死性筋膜炎是一种罕见疾病,其特征为暴发性感染,可导致皮下组织和筋膜平面广泛坏死,死亡率和发病率都很高。其感染源通常为牙源性或咽源性,涉及多种微生物菌群。下行性感染和纵隔受累通常相关,且是主要并发症。本研究的目的是回顾我科治疗的病例,分析诊断和治疗情况,以补充对该疾病的认识。

方法

对2005年1月至2010年6月间入住我中心且诊断为颈部坏死性筋膜炎的患者临床记录进行回顾性研究。

结果

共回顾了6份临床记录。感染源主要为口咽和牙源性,菌群包括普雷沃菌属、消化链球菌属和凝固酶阴性葡萄球菌。所有患者均有纵隔受累:4例为上纵隔炎,2例为上纵隔炎合并后下纵隔炎。所有患者均早期行双侧颈部切开引流,上纵隔受累者经颈部途径行纵隔引流,后下纵隔炎患者在单一手术步骤中联合开胸手术。所有病例均行临时气管切开术。所有患者均接受广谱抗生素治疗,平均住院时间为37天。无死亡病例报告。

结论

对于颈部坏死性筋膜炎,早期诊断、联合抗生素及重症监护的手术治疗对于取得良好疗效至关重要。

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