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颈部坏死性筋膜炎:手术结果分析

Cervical Necrotizing Fasciitis: A Surgical Outcome Analysis.

作者信息

Sidam Shaila, Bhagat Abhinav, Chavan Aparna, Sahoo Anjan K

机构信息

Otolaryngology - Head and Neck Surgery, All India Institute of Medical Sciences, Bhopal, Bhopal, IND.

Radiodiagnosis, All India Institute of Medical Sciences, Bhopal, Bhopal, IND.

出版信息

Cureus. 2023 Sep 4;15(9):e44678. doi: 10.7759/cureus.44678. eCollection 2023 Sep.

DOI:10.7759/cureus.44678
PMID:37809201
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10552681/
Abstract

Cervical necrotizing fasciitis is an immensely progressive, difficult-to-diagnose soft tissue infection of the fascial planes, skin, and subcutaneous tissue. It has marked morbidity and mortality. In this case report, we analyzed the risk factors, laboratory indices, and treatment modalities that affect the outcome of this fatal disease. This is a retrospective case series of cases admitted within a short span of six months between January and June 23. The cases were followed up monthly for three months, and the diagnosis was made on a clinical, pathological, radiological, and histopathological basis. All the cases were managed with neck exploration and aggressive surgical debridement in an emergency department, dressing of the wound with hydrogen peroxide and betadine twice daily, triple broad-spectrum antibiotic therapy for polymicrobial infection, and tight glycemic control. There were no complications, and all the patients survived. We report our cases of cervical necrotizing fasciitis that had similar presentations but varied outcomes. Here, we would like to advocate the importance of immediate management in the form of neck exploration and debridement at the earliest after the diagnosis has been established. Hyperglycemia should be brought under control, and daily aseptic dressing with removal of the slough and source of infection would greatly affect the outcome of this deadly disease.

摘要

颈部坏死性筋膜炎是一种进展迅速、难以诊断的筋膜平面、皮肤及皮下组织的软组织感染。它具有显著的发病率和死亡率。在本病例报告中,我们分析了影响这种致命疾病预后的危险因素、实验室指标及治疗方式。这是一项回顾性病例系列研究,研究对象为在1月至6月23日这短短六个月内收治的病例。对这些病例进行了为期三个月的每月随访,并基于临床、病理、放射学及组织病理学做出诊断。所有病例均在急诊科接受颈部探查及积极的手术清创治疗,伤口每日用双氧水和碘伏换药两次,针对混合感染采用三联广谱抗生素治疗,并严格控制血糖。未出现并发症,所有患者均存活。我们报告了颈部坏死性筋膜炎病例,这些病例表现相似但预后各异。在此,我们倡导在确诊后尽早以颈部探查和清创的形式进行即刻处理的重要性。应控制高血糖,每日进行无菌换药以清除坏死组织及感染源,这将极大地影响这种致命疾病的预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b447/10552681/cf3980d1ec5b/cureus-0015-00000044678-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b447/10552681/02e205fd15f7/cureus-0015-00000044678-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b447/10552681/ca51a5499bbe/cureus-0015-00000044678-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b447/10552681/3a521ff56a75/cureus-0015-00000044678-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b447/10552681/e685b0c1c2db/cureus-0015-00000044678-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b447/10552681/e38cb87b5843/cureus-0015-00000044678-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b447/10552681/7cc3f691b007/cureus-0015-00000044678-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b447/10552681/cf3980d1ec5b/cureus-0015-00000044678-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b447/10552681/02e205fd15f7/cureus-0015-00000044678-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b447/10552681/ca51a5499bbe/cureus-0015-00000044678-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b447/10552681/3a521ff56a75/cureus-0015-00000044678-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b447/10552681/e685b0c1c2db/cureus-0015-00000044678-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b447/10552681/e38cb87b5843/cureus-0015-00000044678-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b447/10552681/7cc3f691b007/cureus-0015-00000044678-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b447/10552681/cf3980d1ec5b/cureus-0015-00000044678-i07.jpg

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本文引用的文献

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Cureus. 2022 Dec 10;14(12):e32382. doi: 10.7759/cureus.32382. eCollection 2022 Dec.
2
Cervical necrotizing fasciitis: Systematic review and analysis of 1235 reported cases from the literature.宫颈坏死性筋膜炎:文献报道的 1235 例病例的系统回顾和分析。
Head Neck. 2018 Sep;40(9):2094-2102. doi: 10.1002/hed.25184. Epub 2018 Jun 22.
3
Current concepts in the management of necrotizing fasciitis.坏死性筋膜炎治疗的当前概念
Front Surg. 2014 Sep 29;1:36. doi: 10.3389/fsurg.2014.00036. eCollection 2014.
4
Cervical necrotizing fasciitis: report of 6 cases and review of literature.颈部坏死性筋膜炎:6例报告并文献复习
Eur Ann Otorhinolaryngol Head Neck Dis. 2014 Dec;131(6):357-359. doi: 10.1016/j.anorl.2013.08.006. Epub 2014 Jul 4.
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Necrotizing fasciitis of the head and neck: surgical outcomes in three cases.头颈部坏死性筋膜炎:三例手术结果
Malays J Med Sci. 2010 Apr;17(2):51-5.
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Is there association between severe multispace infections of the oral maxillofacial region and diabetes mellitus?口腔颌面部严重多间隙感染与糖尿病之间是否存在关联?
J Oral Maxillofac Surg. 2012 Jul;70(7):1565-72. doi: 10.1016/j.joms.2011.07.010. Epub 2011 Oct 19.
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Cervical necrotizing fasciitis: an unusual sequel of odontogenic infection.颈部坏死性筋膜炎:牙源性感染的一种罕见后遗症。
Med Oral Patol Oral Cir Bucal. 2008 Dec 1;13(12):E788-91.