季节性流感与疫苗群体效应。
Seasonal influenza and vaccine herd effect.
作者信息
Kim Tae Hyong
机构信息
Division of Infectious Diseases, Department of Internal Medicine, Soonchunhyang University College of Medicine, Seoul, Korea.
出版信息
Clin Exp Vaccine Res. 2014 Jul;3(2):128-32. doi: 10.7774/cevr.2014.3.2.128. Epub 2014 Jun 20.
Abstract
The seasonal influenza vaccine programs in many regions aimed to protect most vulnerable population, but current trivalent influenza vaccine does not provide sufficient effectiveness among people under high risk for severe outcome of the influenza. The vaccine herd effect (VHE) is the extra protection of non-immune high risk persons, with increase of immunity among vaccinated healthier persons which prevents circulation of influenza in the community. Accumulating evidences are supporting the immunization of extended population with regard to the VHE.
摘要
许多地区的季节性流感疫苗计划旨在保护最脆弱人群，但目前的三价流感疫苗在流感重症高危人群中并未提供足够的有效性。疫苗群体效应（VHE）是指对未免疫的高危人群的额外保护，随着接种疫苗的健康人群免疫力的提高，可防止流感在社区传播。越来越多的证据支持基于疫苗群体效应扩大免疫接种人群。
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