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疾病与日常生活:慢性精神分裂症中精神病理综合征与社会心理功能的密切相互作用。

The illness and everyday living: close interplay of psychopathological syndromes and psychosocial functioning in chronic schizophrenia.

机构信息

LWL University Hospital, Department of Psychiatry, Psychotherapy, Psychosomatics and Preventive Medicine, Ruhr University Bochum, Alexandrinenstr. 1, 44791 Bochum, Germany.

出版信息

Eur Arch Psychiatry Clin Neurosci. 2011 Mar;261(2):85-93. doi: 10.1007/s00406-010-0122-1. Epub 2010 Jul 22.

Abstract

The interaction of psychopathological states and psychosocial functioning determine the long-term course of schizophrenia and its treatment. To be able to achieve this interplay better, exact assessment of psychosocial functioning is needed besides measurement of psychopathology. Using the Personal and Social Performance (PSP) Scale, examination of the association between psychosocial functioning and psychopathology was conducted in a sample of 103 patients with chronic schizophrenia. Rating instruments were in addition Global Assessment of Functioning Scale and Social and Occupational Functioning Assessment Scale, as well as Positive and Negative Syndrome Scale (PANSS), Clinical Global Impression Scale, and Mini-ICF-APP-Rating for Mental Disorders (Mini-ICF-APP). Besides good psychometric properties for the PSP scale in this chronic sample, we found, as expected, significant associations between the two relevant outcome domains: results showed significant negative correlations between PSP and PANSS. Findings prove the close interplay between social functioning and psychopathology in the chronic course of schizophrenia.

摘要

精神病理状态和心理社会功能的相互作用决定了精神分裂症的长期病程及其治疗。为了更好地实现这种相互作用,除了测量精神病理学外,还需要对心理社会功能进行精确评估。本研究使用个人和社会表现量表(PSP),对 103 例慢性精神分裂症患者的心理社会功能和精神病理学之间的相关性进行了研究。评估工具除了一般功能评估量表和社会及职业功能评估量表外,还有阳性和阴性症状量表(PANSS)、临床总体印象量表和精神障碍的微型国际功能、残疾和健康分类应用程序评定量表(Mini-ICF-APP-R)。除了 PSP 量表在慢性样本中的良好心理测量学特性外,我们还发现,正如预期的那样,两个相关的结果领域之间存在显著的相关性:结果显示 PSP 和 PANSS 之间存在显著的负相关。研究结果证明了在慢性精神分裂症病程中社会功能和精神病理学之间的密切相互作用。

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