Ahmed Imtiaz, Krishnamurthy Sapna, Kakkar Aanchal, Julka Pramod Kumar, Rath Goura Kishor
Department of Radiotherapy and Oncology, All India Institute of Medical Sciences, New Delhi, India.
Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.
Indian J Med Paediatr Oncol. 2014 Jan;35(1):86-8. doi: 10.4103/0971-5851.133729.
A 6½-year-old boy had developed acute lymphoblastic leukemia and was treated with systemic chemotherapy, intrathecal triple drug regimen and prophylactic cranial irradiation. After 10 years he developed anaplastic astrocytoma of the postero-superior cerebellum on the left side while leukemia was in remission. He was treated with surgical excision, followed by adjuvant three dimensional conformal radiotherapy and is on salvage chemotherapy with temozolamide. It is possible that the anaplastic astrocytoma may be a radiation induced malignancy.
一名6岁半的男孩患急性淋巴细胞白血病，接受了全身化疗、鞘内三联药物治疗方案和预防性颅脑照射。10年后，白血病缓解期时，他左侧小脑后上部出现间变性星形细胞瘤。他接受了手术切除，随后进行辅助三维适形放疗，并正在接受替莫唑胺挽救化疗。间变性星形细胞瘤有可能是辐射诱发的恶性肿瘤。
