Mcmullin Christine M, Morton Jonathan, Vickramarajah Saranya, Cameron Ewen, Parkes Miles, Torrente Franco, Heuschkel Robert, Carroll Nicholas, Davies R Justin
Cambridge Colorectal Unit, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0QQ, UK.
Department of Gastroenterology, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0QQ, UK.
ISRN Gastroenterol. 2014 Mar 27;2014:410753. doi: 10.1155/2014/410753. eCollection 2014.
Background. The incidence of inflammatory bowel disease (IBD) is increasing in the paediatric population. Since 2007, a single surgeon whose main practice is in the treatment of adults has performed surgery for IBD in adults and children within two dedicated multidisciplinary teams. Our aim was to assess and compare outcomes for adults and children following surgery for IBD. Methods. Analysis of a prospectively collected database was carried out to include all patients who had undergone resectional surgery for IBD between 2007 and 2012. Results. 48 adults and 30 children were included in the study. Median age for children was 14 years (range 8-16) and for adults was 33.5 years (range 17-64). Median BMI was 23 (range 18-38) and 19 (range 13-29.5) in adults and children, respectively (P < 0.001). Laparoscopic resection was performed in 27 (90%) children and 36 (75%) adults. Postoperative complication rates were comparable, 11 (23%) in adults versus 6 (20%) in children (P = 1.00). Conclusion. Resectional surgery for IBD in children has outcomes that compare favourably with the adult population, with the majority of cases being performed by a laparoscopic approach.
背景。炎症性肠病(IBD)在儿科人群中的发病率正在上升。自2007年以来,一名主要从事成人治疗的外科医生在两个专门的多学科团队中为成人和儿童进行IBD手术。我们的目的是评估和比较IBD手术后成人和儿童的结局。方法。对前瞻性收集的数据库进行分析,纳入2007年至2012年间所有接受IBD切除手术的患者。结果。该研究纳入了48名成人和30名儿童。儿童的中位年龄为14岁(范围8 - 16岁),成人为33.5岁(范围17 - 64岁)。成人和儿童的中位BMI分别为23(范围18 - 38)和19(范围13 - 29.5)(P < 0.001)。27名(90%)儿童和36名(75%)成人进行了腹腔镜切除术。术后并发症发生率相当,成人中为11例(23%),儿童中为6例(20%)(P = 1.00)。结论。儿童IBD切除手术的结局与成人相当,大多数病例采用腹腔镜手术方式。