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腹腔镜时代的炎症性肠病手术治疗。

Surgery for inflammatory bowel disease in the era of laparoscopy.

出版信息

World J Gastroenterol. 2013 Apr 28;19(16):2445-8. doi: 10.3748/wjg.v19.i16.2445.

Abstract

During the course of inflammatory bowel disease (IBD), surgery may be needed. Approximately 20% of patients with ulcerative colitis (UC) will require surgery, whereas up to 80% of Crohn's disease (CD) patients will undergo an operation during their lifetime. For UC patients requiring surgery, total proctocolectomy and ileoanal pouch anastomosis (IPAA) is the operation of choice as it provides a permanent cure and good quality of life. Nevertheless a permanent stoma is a good option in selected patients, especially the elderly. Minimally invasive surgery has replaced the conventional open approach in many specialized centres worldwide. Laparoscopic colectomy and restorative IPAA is rapidly becoming the standard of care in the treatment of UC requiring surgery, whilst laparoscopic ileo-cecal resection is already the new gold standard in the treatment of complicated CD of terminal ileum. Short term advantages of laparoscopic surgery includes faster recovery time and reduced requirement for analgesics. It is, however, in the long term that minimally invasive surgery has demonstrated its superiority over the open approach. A better cosmesis, a reduced number of incisional hernias and fewer adhesions are the long term advantages of laparoscopy in IBD surgery. A reduction in abdominal adhesions is of great benefit when a second operation is needed in CD and this influences positively the pregnancy rate in young women undergoing restorative IPAA. In developing the therapeutic plan for IBD patients it should be recognized that the surgical approach to the abdomen has changed and that surgical treatment of complicated IBD can be safely performed with a true minimally invasive approach with great patient satisfaction.

摘要

在炎症性肠病(IBD)的病程中,可能需要手术。大约 20%的溃疡性结肠炎(UC)患者需要手术,而多达 80%的克罗恩病(CD)患者在其一生中会进行手术。对于需要手术的 UC 患者,全结肠直肠切除术和回肠肛管吻合术(IPAA)是首选手术,因为它提供了永久性治愈和良好的生活质量。然而,对于某些患者,尤其是老年人,永久性造口术是一个不错的选择。微创外科已在全球许多专业中心取代了传统的开放方法。腹腔镜结肠切除术和修复性 IPAA 迅速成为需要手术治疗的 UC 的标准治疗方法,而腹腔镜回盲肠切除术已经成为治疗末端回肠复杂 CD 的新标准。腹腔镜手术的短期优势包括恢复时间更快,对镇痛药的需求减少。然而,正是在长期,微创外科已经证明了其优于开放方法的优势。在 IBD 手术中,腹腔镜具有更好的美容效果、更少的切口疝和更少的粘连等长期优势。当 CD 需要再次手术时,减少腹部粘连具有很大的益处,这对接受修复性 IPAA 的年轻女性的妊娠率有积极影响。在制定 IBD 患者的治疗计划时,应该认识到腹部的手术方法已经发生了变化,并且可以通过真正的微创方法安全地对复杂的 IBD 进行手术治疗,从而获得患者的高度满意度。

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