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肺动脉高压和间质性肺疾病中的抑郁。

Depression in pulmonary arterial hypertension and interstitial lung diseases.

作者信息

Verma Sameer, Cardenas-Garcia Jose, Mohapatra Prasanta R, Talwar Arunabh

机构信息

Department of Pulmonary, Critical Care and Sleep Medicine, North Shore - Long Island Jewish Health System, New York, USA.

Department of Pulmonary Medicine, All India Institute of Medical Sciences, Sijua, Bhubaneswar, Odisha, India.

出版信息

N Am J Med Sci. 2014 Jun;6(6):240-9. doi: 10.4103/1947-2714.134368.

DOI:10.4103/1947-2714.134368
PMID:25006558
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4083524/
Abstract

Advanced lung diseases such as pulmonary arterial hypertension (PAH) and interstitial lung diseases (ILD) are chronic diseases that cause significantly high morbidity and mortality. As a result, patients can undergo some psychological changes leading to a poor quality of life and depression. Diagnosis of depression is often obscured because fatigue and apathy, two common symptoms of depression, frequently overlap with PAH and ILD. Healthcare providers are sometimes reluctant to ask or mistakenly believe that these symptoms are part of the ongoing disease process, rather than a serious condition like depression. Screening tools are available for physicians to be well positioned in recognizing clinical depression in PAH and ILD. A MedLine/PubMED search was performed identifying all relevant articles with "PAH", "ILD", "screening tools" and/or "Depression" in the title. The aim of this review is to provide a brief description of some of the instruments used to screen patients and classes of psychotropic medications accessible to physicians. While pulmonary rehabilitation programs can have a positive impact on patients, physicians should also utilize cognitive behavioral therapy (CBT) as part of regular care.

摘要

诸如肺动脉高压(PAH)和间质性肺疾病(ILD)等晚期肺部疾病是导致高发病率和高死亡率的慢性疾病。因此,患者可能会出现一些心理变化,导致生活质量下降和抑郁。抑郁症的诊断常常被掩盖,因为疲劳和冷漠这两种抑郁症的常见症状经常与PAH和ILD重叠。医疗保健提供者有时不愿询问,或者错误地认为这些症状是当前疾病过程的一部分,而不是像抑郁症这样的严重病症。有一些筛查工具可供医生使用,以便更好地识别PAH和ILD患者的临床抑郁症。我们进行了一项医学在线/医学期刊数据库(MedLine/PubMED)搜索,找出标题中包含“PAH”、“ILD”、“筛查工具”和/或“抑郁症”的所有相关文章。本综述的目的是简要介绍一些用于筛查患者的工具以及医生可使用的精神药物类别。虽然肺康复计划可以对患者产生积极影响,但医生也应将认知行为疗法(CBT)作为常规护理的一部分加以利用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/675d/4083524/00ed5e9163b9/NAJMS-6-240-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/675d/4083524/fa7160597913/NAJMS-6-240-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/675d/4083524/76d101d0b7a6/NAJMS-6-240-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/675d/4083524/00ed5e9163b9/NAJMS-6-240-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/675d/4083524/fa7160597913/NAJMS-6-240-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/675d/4083524/76d101d0b7a6/NAJMS-6-240-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/675d/4083524/00ed5e9163b9/NAJMS-6-240-g005.jpg

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本文引用的文献

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Understanding the impact of pulmonary arterial hypertension on patients' and carers' lives.了解肺动脉高压对患者及其照护者生活的影响。
Eur Respir Rev. 2013 Dec;22(130):535-42. doi: 10.1183/09059180.00005713.
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Use of selective serotonin reuptake inhibitors and outcomes in pulmonary arterial hypertension.选择性 5-羟色胺再摄取抑制剂在肺动脉高压中的应用及疗效。
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The burden of comorbidities in pulmonary arterial hypertension.肺动脉高压中共病的负担。
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Measures of depression and depressive symptoms: Beck Depression Inventory-II (BDI-II), Center for Epidemiologic Studies Depression Scale (CES-D), Geriatric Depression Scale (GDS), Hospital Anxiety and Depression Scale (HADS), and Patient Health Questionnaire-9 (PHQ-9).抑郁及抑郁症状的测量工具:贝克抑郁量表第二版(BDI-II)、流行病学研究中心抑郁量表(CES-D)、老年抑郁量表(GDS)、医院焦虑抑郁量表(HADS)以及患者健康问卷-9(PHQ-9)。
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