Kohorst John J, Hagen Clinton, Baum Christian L, Davis Mark D P
J Drugs Dermatol. 2014 Jul;13(7):827-31.
Treatment of hidradenitis suppurativa has been studied, but treatment strategies and outcomes have not been reported for a large community-based group of patients.
We sought to determine the treatments most commonly prescribed and the performance of all systemic and surgical treatments used in hidradenitis suppurativa patients in Olmsted County, Minnesota, treated over a 40-year period.
A retrospective chart review was performed to evaluate hidradenitis suppurativa treatments in 376 episodes with 115 Olmsted County patients seen by a clinician at Mayo Clinic in Rochester, Minnesota, between 1968 and 2008. Treatment episode outcomes were recorded from clinical notes for the 73 treatment episodes that had a follow-up period of more than 30 days.
Systemic antibiotics alone were prescribed most frequently in 70.0% of episodes. Systemic antibiotics alone improved 39 of 49 treatment episodes (79.6%), including 13 episodes (26.5%) when the disease was fully cleared. All 5 of 5 episodes (100%) of surgical treatment alone improved, including 4 (80%) in which the disease was fully cleared. Surgery in combination with systemic antibiotic treatment yielded improvement in 5 episodes (71.4%), with 2 episodes (28.6%) showing complete clearance.
Systemic antibiotics were the most frequently prescribed treatment type in 115 patients over a 40-year period. Both systemic antibiotic therapy and surgical treatment are effective in disease management.
化脓性汗腺炎的治疗已得到研究，但尚未有针对大量社区患者群体的治疗策略及结果的报道。
我们试图确定明尼苏达州奥尔姆斯特德县在40年期间接受治疗的化脓性汗腺炎患者最常使用的治疗方法以及所有全身治疗和手术治疗的效果。
进行了一项回顾性病历审查，以评估1968年至2008年间在明尼苏达州罗切斯特市梅奥诊所由临床医生诊治的115名奥尔姆斯特德县患者的376次化脓性汗腺炎治疗情况。从临床记录中记录了73次随访期超过30天的治疗情况的结果。
70.0%的治疗情况最常单独开具全身用抗生素。单独使用全身用抗生素使49次治疗中的39次（79.6%）病情改善，其中1月份3次（26.5%）疾病完全清除。单独进行的5次手术治疗全部改善（100%），其中4次（80%）疾病完全清除。手术联合全身用抗生素治疗使5次治疗情况改善（71.4%），2次（28.6%）完全清除。
在40年期间，全身用抗生素是115名患者最常开具的治疗类型。全身用抗生素治疗和手术治疗在疾病管理中均有效。
