Zheng Ju-Sheng, Liu Huijuan, Li Jing, Chen Yu, Wei Chunlei, Shen Genmei, Zhu Shanlin, Chen Hua, Zhao Yi-Min, Huang Tao, Li Duo
Department of Food Science and Nutrition, Zhejiang University, Hangzhou, China.
Jiaxing Maternity and Child Health Care Hospital, Jiaxing, China; and.
J Nutr. 2014 Sep;144(9):1454-9. doi: 10.3945/jn.114.193664. Epub 2014 Jul 9.
The association between breastfeeding status and childhood overweight is inconclusive. The aim of the present study was to investigate the relation between exclusive breastfeeding and childhood overweight risk in children 4-5 y of age in Southeast China. Among 97,424 children enrolled between 1999 and 2009 in the Jiaxing Birth Cohort, 42,550 of them were included in the final analysis with complete records on breastfeeding status and anthropometric measurements at 4-5 y of age (48-60 mo). Overweight and being at risk of overweight were identified as a body mass index (BMI)-for-age Z-score ≥ 2 and between 1 and 2, respectively. After 4-5 y of follow-up, 4845 (11.4%) children were identified as being at risk of overweight, and 1343 (3.16%) children were overweight. Adjusting for important child and maternal characteristics, longer duration of breastfeeding was associated with lower risk of childhood overweight (P-trend = 0.009) and being at risk of overweight (P-trend < 0.001). Children exclusively breastfed for 3-5 mo and ≥6 mo had 13% (RR = 0.87; 95% CI: 0.77, 0.99) and 27% (RR = 0.73; 95% CI: 0.56, 0.95) lower risk of becoming overweight compared with children exclusively breastfed for <1 mo, respectively. In boys, there were inverse associations of 3-5 mo (RR = 0.83; 95% CI: 0.71, 0.98) or ≥6 mo (RR = 0.65; 95% CI: 0.47, 0.91) of exclusive breastfeeding against becoming overweight, but there were no significant associations in girls (3-5 mo: RR = 0.96, 95% CI: 0.76, 1.22; ≥6 mo: RR = 0.92, 95% CI: 0.60, 1.41). In conclusion, the present findings suggest that longer duration of exclusive breastfeeding is associated with lower risk of becoming overweight in Chinese children.
母乳喂养状况与儿童期超重之间的关联尚无定论。本研究的目的是调查中国东南部4至5岁儿童纯母乳喂养与儿童期超重风险之间的关系。在1999年至2009年纳入嘉兴出生队列的97424名儿童中，42550名儿童因拥有关于母乳喂养状况和4至5岁（48至60个月）时人体测量的完整记录而被纳入最终分析。超重和有超重风险分别被定义为年龄别体重指数（BMI）Z评分≥2和在1至2之间。经过4至5年的随访，4845名（11.4%）儿童被确定有超重风险，1343名（3.16%）儿童超重。在对重要的儿童和母亲特征进行调整后，母乳喂养时间越长，儿童期超重风险越低（P趋势=0.009）以及有超重风险的可能性越低（P趋势<0.001）。与纯母乳喂养时间<1个月的儿童相比，纯母乳喂养3至5个月和≥6个月的儿童超重风险分别降低了13%（RR=0.87；95%CI：0.77，0.99）和27%（RR=0.73；95%CI：0.56，0.95）。在男孩中，纯母乳喂养3至5个月（RR=0.83；95%CI：0.71，0.98）或≥6个月（RR=0.65；95%CI：0.47，0.91）与超重呈负相关，但女孩中无显著关联（3至5个月：RR=0.96，95%CI：0.76，1.22；≥6个月：RR=0.92，95%CI：0.60，1.41）。总之，目前的研究结果表明，较长时间的纯母乳喂养与中国儿童超重风险较低有关。
