Konings W N, Poolman B, Driessen A J
Department of Microbiology, University of Groningen, Haren, The Netherlands.
Crit Rev Microbiol. 1989;16(6):419-76. doi: 10.3109/10408418909104474.
During the last few years the studies about the physiology and bioenergetics of lactic acid bacteria during growth and starvation have evolved from a descriptive level to an analysis of the molecular events in the regulation of various processes. Considerable progress has been made in the understanding of the modes of metabolic energy generation, the mechanism of homeostasis of the internal pH, and the mechanism and regulatory processes of transport systems for sugars, amino acids, peptides, and ions. Detailed studies of these transport processes have been performed in cytoplasmic membrane vesicles of these organisms in which a foreign proton pump has been introduced to generate a high proton motive force.
在过去几年中,关于乳酸菌在生长和饥饿期间的生理学和生物能量学的研究已从描述层面发展到对各种过程调控中分子事件的分析。在理解代谢能量产生模式、内部pH稳态机制以及糖、氨基酸、肽和离子转运系统的机制和调控过程方面取得了相当大的进展。已在这些生物体的细胞质膜囊泡中对这些转运过程进行了详细研究,其中引入了外源质子泵以产生高质子动力势。