Feng Bin, Cheng Hong-Gang, Chen Jia-Rong, Deng Qiao-Hui, Lu Liang-Qiu, Xiao Wen-Jing
Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, 152 Luoyu Road, Wuhan, Hubei 430079, China.
Chem Commun (Camb). 2014 Aug 28;50(67):9550-3. doi: 10.1039/c4cc03920c.
The Pd/sulfoxide-phosphine-catalyzed highly enantioselective allylic etherification and amination with a wide range of O- and N-nucleophiles have been developed (up to 97% yield, 98.5% ee). The products can also be conveniently transformed into biologically active chiral heterocycles.
已开发出钯/亚砜-膦催化的、与多种O-和N-亲核试剂进行的高对映选择性烯丙基醚化和胺化反应（产率高达97%，对映体过量值高达98.5%）。产物还可方便地转化为具有生物活性的手性杂环化合物。
