Thakur B K, Verma S, Mishra J
Department of Dermatology and STD, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, India
Department of Dermatology and STD, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, India.
Int J STD AIDS. 2015 Jun;26(7):512-5. doi: 10.1177/0956462414543123. Epub 2014 Jul 10.
Human immunodeficiency virus-infected patients are at increased risk of drug reactions because of immune dysregulation and multiple drug intake. Lichenoid drug reactions to isoniazid have been reported previously in the literature. However, for lichenoid drug reaction to isoniazid to be so extensive to present as exfoliative dermatitis is rare. We report here a rare case of lichenoid drug reaction to isoniazid presenting as exfoliative dermatitis in a patient with acquired immunodeficiency syndrome.
由于免疫失调和多种药物摄入，感染人类免疫缺陷病毒的患者发生药物反应的风险增加。先前文献中已有关于异烟肼引起苔藓样药物反应的报道。然而，异烟肼引起的苔藓样药物反应广泛到表现为剥脱性皮炎的情况罕见。我们在此报告一例获得性免疫缺陷综合征患者中，异烟肼引起的苔藓样药物反应表现为剥脱性皮炎的罕见病例。
