Kim Jakyoung, Park Shinyoung, Jung Chul Min, Oh Chee Won, Kwon Jae Woo
Department of Pediatrics, Kangwon National University School of Medicine, Chuncheon, Korea.
The Research Department, Kangwon Regional Cancer Center, Kangwon National University Hospital, Chuncheon, Korea.
Allergy Asthma Immunol Res. 2017 May;9(3):281-284. doi: 10.4168/aair.2017.9.3.281.
Lichenoid drug eruption (LDE) is a rare form of delayed-type drug eruption. Among anti-tuberculosis (Tb) agents, cycloserine (CS) has been reported as a rare cause of LDE. Positive results on the lymphocyte transformation test (LTT) have not been reported in patients with LDE. In the present case, we performed LTT and a patch test, and successfully proved CS as the offending drug in this patient, who had been treated with multiple anti-Tb drugs. These observations suggest that CS should be considered a possible cause of LDE and that LTT can be an option for the diagnosis of LDE.
苔藓样药疹（LDE）是一种罕见的迟发型药疹。在抗结核药物中，环丝氨酸（CS）已被报道为LDE的罕见病因。尚未有LDE患者淋巴细胞转化试验（LTT）呈阳性结果的报道。在本病例中，我们进行了LTT和斑贴试验，并成功证实CS是该接受多种抗结核药物治疗患者的致病药物。这些观察结果表明，CS应被视为LDE的可能病因，且LTT可作为LDE诊断的一种选择。
