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开发用于生物电位测量的带倒刺微尖端电极阵列。

Developing barbed microtip-based electrode arrays for biopotential measurement.

作者信息

Hsu Li-Sheng, Tung Shu-Wei, Kuo Che-Hsi, Yang Yao-Joe

机构信息

Department of Mechanical Engineering, National Taiwan University, Taipei 10617, Taiwan.

出版信息

Sensors (Basel). 2014 Jul 10;14(7):12370-86. doi: 10.3390/s140712370.

Abstract

This study involved fabricating barbed microtip-based electrode arrays by using silicon wet etching. KOH anisotropic wet etching was employed to form a standard pyramidal microtip array and HF/HNO3 isotropic etching was used to fabricate barbs on these microtips. To improve the electrical conductance between the tip array on the front side of the wafer and the electrical contact on the back side, a through-silicon via was created during the wet etching process. The experimental results show that the forces required to detach the barbed microtip arrays from human skin, a polydimethylsiloxane (PDMS) polymer, and a polyvinylchloride (PVC) film were larger compared with those required to detach microtip arrays that lacked barbs. The impedances of the skin-electrode interface were measured and the performance levels of the proposed dry electrode were characterized. Electrode prototypes that employed the proposed tip arrays were implemented. Electroencephalogram (EEG) and electrocardiography (ECG) recordings using these electrode prototypes were also demonstrated.

摘要

本研究涉及通过硅湿法蚀刻制造带倒刺微尖端的电极阵列。采用KOH各向异性湿法蚀刻形成标准的金字塔形微尖端阵列,并使用HF/HNO3各向同性蚀刻在这些微尖端上制造倒刺。为了提高晶圆正面的尖端阵列与背面的电触点之间的电导率,在湿法蚀刻过程中创建了一个硅通孔。实验结果表明,与去除无倒刺微尖端阵列所需的力相比,将带倒刺微尖端阵列从人体皮肤、聚二甲基硅氧烷(PDMS)聚合物和聚氯乙烯(PVC)薄膜上分离所需的力更大。测量了皮肤-电极界面的阻抗,并对所提出的干电极的性能水平进行了表征。实现了采用所提出的尖端阵列的电极原型。还展示了使用这些电极原型进行的脑电图(EEG)和心电图(ECG)记录。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0d8/4168478/c52f28a6bc7b/sensors-14-12370f1.jpg

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