Departamento de Tecnología Química y Ambiental, Tecnología Química y Energética, Tecnología Mecánica y Química Analítica, E.S.C.E.T, Universidad Rey Juan Carlos, C/Tulipán s/n, Móstoles, 28933 Madrid, Spain.
Departamento de Tecnología Química y Ambiental, Tecnología Química y Energética, Tecnología Mecánica y Química Analítica, E.S.C.E.T, Universidad Rey Juan Carlos, C/Tulipán s/n, Móstoles, 28933 Madrid, Spain.
J Chromatogr A. 2014 Oct 10;1363:27-40. doi: 10.1016/j.chroma.2014.06.063. Epub 2014 Jun 24.
Recent advances in the development of new materials are having a major impact on analytical chemistry. For example, the unique properties of ordered mesoporous silicas (OMSs) have been shown to enhance the analytical performance of many existing techniques or allow new, exciting ones to be developed. Likewise, the introduction of organo-functional groups makes OMSs highly versatile and enables them to perform specialized tasks, such as the separation of chiral compounds. This review provides an overview with the most relevant achievements in the preparation of OMS particles functionalized with chiral selectors. In addition, some examples from the last fifteen years regarding the analytical applications of functionalized OMS for chiral separations by high-performance liquid chromatography, ultra-high pressure high-performance liquid chromatography and capillary electrochromatography have been reviewed.
新材料的发展进展对分析化学产生了重大影响。例如，有序介孔硅（OMS）的独特性质已被证明可以提高许多现有技术的分析性能，或者允许开发新的令人兴奋的技术。同样，有机官能团的引入使 OMS 具有高度的多功能性，并能够执行特殊任务，例如手性化合物的分离。本综述提供了一个概述，介绍了用手性选择剂功能化的 OMS 颗粒的最相关的成就。此外，还回顾了过去十五年中有关通过高效液相色谱、超高压高效液相色谱和毛细管电色谱对手性分离进行功能化 OMS 的分析应用的一些实例。
