Costilla Vanessa C, Foxx-Orenstein Amy E
Department of Internal Medicine, Mayo Clinic in Arizona, Scottsdale, AZ, USA,
Curr Treat Options Gastroenterol. 2014 Sep;12(3):310-21. doi: 10.1007/s11938-014-0025-8.
Symptoms of constipation occur at all ages, with the greatest prevalence in individuals older than 60 years of age. It is estimated that 35 million individuals suffer from constipation in the USA, but only a small number will ever be diagnosed. Patients identify constipation symptoms differently than physicians. Whereas a patient may define their constipation by symptoms of bloating, distension, feeling of incomplete evacuation, abdominal discomfort, hard stools, and excessive straining, physicians often interpret prolonged timing between movements as the most essential criteria. An evaluation of constipation begins with a focused history of a person's bowel habit, medications, diet, physical activity, and an anorectal examination. In the absence of alarm signs, diagnostic testing for constipation is not routinely recommended in the initial evaluation. First-line management includes lifestyle changes of increased physical activity, high-fiber diets, adequate fluid intake, and bowel management techniques such as a straight back sitting position, using known triggers to stimulate bowel contractions, and a foot stool to elevate knees above bottom during toileting. When refractory to initial management, patients should have anorectal manometry to assess outlet function; additional testing may be required. Biofeedback is an effective treatment option for dyssynergic defecation. A range of traditional and new pharmacologic therapies are available to remedy constipation, from stool softeners to agents that increase intestinal transit. Managing the primary and secondary causes of constipation, incorporating effective bowel management techniques, along with the judicious use of laxatives can reduce constipation symptoms and improve quality of life.
便秘症状在各年龄段均有发生,60岁以上人群中患病率最高。据估计,美国有3500万人患有便秘,但只有少数人会被诊断出来。患者对便秘症状的界定与医生不同。患者可能会根据腹胀、腹部膨隆、排便不尽感、腹部不适、大便干结及过度用力等症状来定义便秘,而医生通常将排便间隔时间延长视为最关键的标准。对便秘的评估始于详细了解个人的排便习惯、用药情况、饮食、身体活动情况以及进行肛肠检查。在没有警示征象的情况下,初始评估时通常不建议对便秘进行诊断性检查。一线治疗措施包括改变生活方式,如增加身体活动、采用高纤维饮食、保证充足的液体摄入,以及采用排便管理技巧,如挺直背部坐姿、利用已知的刺激因素来刺激肠道收缩,如厕时使用脚凳将膝盖抬高至臀部上方。如果初始治疗效果不佳,患者应接受肛肠测压以评估出口功能;可能还需要进行其他检查。生物反馈是治疗排便协同失调的有效方法。从大便软化剂到增加肠道蠕动的药物,有一系列传统和新型药物疗法可用于治疗便秘。处理便秘的主要和次要病因,结合有效的排便管理技巧,以及合理使用泻药,可以减轻便秘症状并改善生活质量。