Epstein Kira L
Department of Large Animal Medicine, College of Veterinary Medicine, University of Georgia, 501 DW Brooks Dr, Athens, GA 30602, USA.
Vet Clin North Am Equine Pract. 2014 Aug;30(2):437-52, ix. doi: 10.1016/j.cveq.2014.04.002. Epub 2014 Jun 4.
Although primary coagulopathies are rare in horses, changes in coagulation and fibrinolysis are commonly associated with inflammatory diseases. A clear understanding of the pathophysiology of normal and abnormal hemostasis is required to be able to choose and interpret diagnostic tests evaluating coagulation and fibrinolysis. After diagnosis, treatment of the underlying disease must occur regardless of whether clinical manifestations (excessive bleeding or thrombosis) of the coagulopathy are present or not. Specific treatment may be initiated if there are clinical signs of coagulopathy.
虽然原发性凝血障碍在马匹中很少见,但凝血和纤维蛋白溶解的变化通常与炎症性疾病有关。为了能够选择和解释评估凝血和纤维蛋白溶解的诊断测试,需要清楚了解正常和异常止血的病理生理学。诊断后,无论是否存在凝血障碍的临床表现(出血过多或血栓形成),都必须对基础疾病进行治疗。如果有凝血障碍的临床症状,可开始进行特异性治疗。