Caubet Jean-Christoph, Ponvert Claude
Department of Pediatrics, University Hospitals of Geneva and Medical School, University of Geneva, Geneva, Switzerland.
Pulmonology & Allergology Service, Department of Pediatrics, Sick Children's Hospital, Paris, France.
Immunol Allergy Clin North Am. 2014 Aug;34(3):597-613, ix. doi: 10.1016/j.iac.2014.04.004.
Overdiagnosis of vaccine allergy is considered a major public health problem. This article discusses the different types of allergic reactions after immunization based on the timing (immediate vs nonimmediate) and the extent of the reaction (local vs systemic). The vaccine components potentially responsible for an allergic reaction are discussed, as well as the management of patients with a history of reaction to a specific vaccine and those with a history of allergy to one of the vaccine components.
疫苗过敏的过度诊断被认为是一个重大的公共卫生问题。本文根据反应发生的时间（即刻与非即刻）和反应程度（局部与全身），讨论了免疫接种后不同类型的过敏反应。文中还讨论了可能导致过敏反应的疫苗成分，以及有特定疫苗反应史的患者和对疫苗成分之一有过敏史的患者的管理方法。
