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[对有疫苗成分过敏反应风险儿童进行安全疫苗接种的建议]

[Recommendations for safe vaccination in children at the risk of taking allergic reactions to vaccine components].

出版信息

Arch Argent Pediatr. 2018 Apr 1;116(2):s34-s47. doi: 10.5546/aap.2018.s34.

DOI:10.5546/aap.2018.s34
PMID:29775037
Abstract

Vaccines are one of the most important advances in medicine as a public health tool for the control of immunopreventable diseases. Occasionally, adverse reactions may occur. If a child has a reaction to a vaccine, it is likely to disrupt his immunization schedule with risks to himself and the community. This establishes the importance of correctly diagnosing a possible allergy and defining appropriate behavior. Allergic reactions to vaccines may be due to the immunogenic component, to the residual proteins in the manufacturing process and to antimicrobial agents, stabilizers, preservatives and any other element used in the manufacturing process. Vaccination should be a priority in the entire child population, so this document describes particular situations of allergic children to minimize the risk of immunizations and achieve safe vaccination.

摘要

疫苗作为控制免疫可预防疾病的公共卫生工具,是医学领域最重要的进展之一。偶尔会出现不良反应。如果儿童对疫苗有反应,很可能会打乱其免疫接种计划,对自身和社区都有风险。这就确立了正确诊断可能的过敏反应并确定适当应对措施的重要性。对疫苗的过敏反应可能归因于免疫原性成分、生产过程中的残留蛋白质、抗菌剂、稳定剂、防腐剂以及生产过程中使用的任何其他元素。疫苗接种应是全体儿童的优先事项,因此本文档描述了过敏儿童的特殊情况,以尽量降低免疫接种风险并实现安全接种。

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