Zheng Zhuoyuan, Li Ye, Cai Yunpeng
Shenzhen Institutes of Advanced Technology and Key Laboratory for Health Informatics, Chinese Academy of Sciences, Shenzhen University Town, 1068 Xueyuan Avenue, Shenzhen 518055, China ; School of Computer Science and Engineering, Guilin University of Electronic Technology, Guilin 541004, China ; University of Chinese Academy of Sciences, No. 19A Yuquan Road, Beijing 100049, China.
Shenzhen Institutes of Advanced Technology and Key Laboratory for Health Informatics, Chinese Academy of Sciences, Shenzhen University Town, 1068 Xueyuan Avenue, Shenzhen 518055, China.
ScientificWorldJournal. 2014;2014:761486. doi: 10.1155/2014/761486. Epub 2014 Jun 15.
Hypertension is a highly prevalent risk factor for cardiovascular disease and it can also lead to other diseases which seriously harm the human health. Screening the risks and finding a clinical model for estimating the risk of onset, maintenance, or the prognosis of hypertension are of great importance to the prevention or treatment of the disease, especially if the indicator can be derived from simple health profile. In this study, we investigate a chronic disease questionnaire data set of 6563 rural citizens in East China and find out a clinical signature that can assess the risk of hypertension easily and accurately. The signature achieves an accuracy of about 83% on the external test dataset, with an AUC of 0.91. Our study demonstrates that a combination of simple lifestyle features can sufficiently reflect the risk of hypertension onset. This finding provides potential guidance for disease prevention and control as well as development of home care and home-care technologies.
高血压是心血管疾病的一种高度普遍的风险因素，它还会导致其他严重危害人类健康的疾病。筛查风险并找到一种用于估计高血压发病、维持或预后风险的临床模型，对于该疾病的预防或治疗非常重要，特别是如果该指标可以从简单的健康状况中得出。在本研究中，我们调查了中国东部6563名农村居民的慢性病调查问卷数据集，并找出了一种能够轻松、准确地评估高血压风险的临床特征。该特征在外部测试数据集上的准确率约为83%，曲线下面积（AUC）为0.91。我们的研究表明，简单的生活方式特征组合可以充分反映高血压发病的风险。这一发现为疾病的预防和控制以及家庭护理和家庭护理技术的发展提供了潜在的指导。
