Xu Gang, Liu Junxiu, Liu Shiwei, Zhou Haiming, Orekoya Olubunmi, Liu Jie, Li Yichong, Tang Ji, Zhou Chunlian, Huang Jiuling
From the Department of Preventive Medicine, School of Basic Medicine, Jiangxi University of Traditional Chinese Medicine, Nanchang, China (GX, JH); Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, South Carolina, USA (JL, OO); National Center for Chronic and Non-communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China (SL, YL); Department of Statistics, University of South Carolina, Columbia, South Carolina, USA (HZ); Division of Chronic Disease Control and Prevention, Jiangxi Province Center for Disease Control and Prevention, Nanchang, Jiangxi, China (JL); Chinese Preventive Medicine Association, Beijing, China (JT); and Department of Nosocomial Infectious Prevention and Control, Beijing Friendship Hospital, Capital Medical University, Beijing, China (CZ).
Medicine (Baltimore). 2015 Sep;94(39):e1623. doi: 10.1097/MD.0000000000001623.
Elevated blood pressure (BP) as a risk factor accounts for the biggest burden of disease worldwide and in China. This study aimed to estimate attributed mortality and life expectancy (LE) to elevated BP in Jiangxi province between 2007 and 2010. BP and mortality data (2007 and 2010 inclusive) were obtained from the National Chronic Diseases and Risk Factors Surveillance Survey and Disease Surveillance Points system, respectively. Population-attributable fraction used in comparative risk assessment of the Global Burden of Disease study 2010 were followed to quantify the attributed mortality to elevated BP, subsequently life table methods were applied to estimate its effects on LE. Uncertainty analysis was conducted to get 95% uncertainty intervals (95% uncertainty interval [UI]) for each outcome. There are 35,482 (95% UI: 31,389-39,928) and 47,842 (42,323-53,837) deaths in Jiangxi province were caused by elevated BP in 2007 and 2010, respectively. 2.24 (1.87-2.65) years of LE would be gained if all the attributed deaths were eliminated in 2007, and increased to 3.04 (2.52-3.48) in 2010. If the mean value of elevated BP in 2010 was decreased by 5 and 10 mm Hg, 5324 (4710-5991) and 11,422 (10,104-12,853) deaths would be avoided, with 0.41 (0.37-0.48) and 0.85 (0.71-1.09) years of LE gained, respectively. The deaths attributable to elevated BP in Jiangxi province has increased by 35% from 2007 to 2010, with 0.8 years of LE loss, suggesting the necessity to take actions to control BP in Chinese population.
高血压作为一个风险因素，在全球和中国都是导致疾病负担最重的因素。本研究旨在估算2007年至2010年间江西省高血压导致的归因死亡率和预期寿命。血压和死亡率数据（包括2007年和2010年）分别来自全国慢性病及危险因素监测调查和疾病监测点系统。采用2010年全球疾病负担研究比较风险评估中使用的人群归因分数来量化高血压导致的归因死亡率，随后应用生命表方法估算其对预期寿命的影响。进行不确定性分析以获得每个结果的95%不确定性区间（95% UI）。2007年和2010年江西省分别有35482例（95% UI：31389 - 39928）和47842例（42323 - 53837）死亡由高血压导致。如果在2007年消除所有归因死亡，预期寿命将增加2.24年（1.87 - 2.65），到2010年增加至3.04年（2.52 - 3.48）。如果2010年高血压的平均值降低5和10毫米汞柱，将分别避免5324例（4710 - 5991）和11422例（10104 - 12853）死亡，预期寿命分别增加0.41年（0.37 - 0.48）和0.85年（0.71 - 1.09）。从2007年到2010年，江西省高血压归因死亡增加了35%，预期寿命损失0.8年，这表明有必要采取行动控制中国人群的血压。
