Burton E M, Ball W S, Crone K, Dolan L M
Department of Radiology, Children's Hospital Medical Center, Cincinnati, OH 45229.
AJNR Am J Neuroradiol. 1989 May-Jun;10(3):497-501.
Hamartoma of the tuber cinereum is a well-recognized cause of central precocious puberty. We report three patients with an isodense, nonenhancing mass within the interpeduncular cistern identified by CT. In a fourth patient, the CT scan was normal. MR imaging was obtained in all cases and demonstrated a sessile or pedunculated mass of the posterior hypothalamus arising from the region of the tuber cinereum. The smallest mass was 2 mm in diameter and was found in the patient in whom the CT scan was normal. The signal intensity of the masses was generally homogeneous and isointense relative to gray matter on T1- and intermediate-weighted images, and hyper-intense on T2-weighted images. MR imaging accurately diagnoses hypothalamic hamartomas, identifies small hamartomas of the tuber cinereum more sensitively than CT does, and provides optimal imaging for serial evaluation while the patient is being treated medically.
灰结节错构瘤是中枢性性早熟的一个公认病因。我们报告了3例经CT检查发现脚间池内等密度、无强化肿块的患者。第4例患者的CT扫描结果正常。所有病例均进行了磁共振成像（MR成像），显示下丘脑后部有一个无蒂或有蒂肿块，起源于灰结节区域。最小的肿块直径为2毫米，在CT扫描正常的患者中发现。肿块的信号强度通常均匀，在T1加权像和中等加权像上相对于灰质呈等信号，在T2加权像上呈高信号。MR成像能准确诊断下丘脑错构瘤，比CT更敏感地识别灰结节小错构瘤，并为患者接受药物治疗期间的系列评估提供最佳成像。
