Guibaud L, Rode V, Saint-Pierre G, Pracros J P, Foray P, Tran-Minh V A
Department of Radiology, Montreal General Hospital, McGill University, PQ, Canada.
Pediatr Radiol. 1995;25(1):17-8. doi: 10.1007/BF02020833.
A case of neonatal manifestation of giant hypothalamic hamartoma is reported. It is suggested that hypothalamic hamartoma should be included in the list of neonatal intracerebral tumors. Magnetic resonance imaging appearance similar to that of normal gray matter on T1-weighted images and slightly hyperintense on T2-weighted images, without enhancement after gadolinium injection, is suggestive of the diagnosis. Hypothalamic hamartomas are congenital malformations, consisting of disorganized mature neuronal elements in proportions similar to that of normal tissue [1]. They are clinically evidenced in infants ranging from 1 to 7 years of age [1-5]. This report describes a histologically proved giant hypothalamic hamartoma diagnosed in the neonatal period. Magnetic resonance imaging (MRI) is helpful to distinguish this congenital non-evolutive malformation from more aggressive neonatal tumors.
本文报告了一例巨大下丘脑错构瘤的新生儿表现。提示下丘脑错构瘤应列入新生儿脑内肿瘤名单。磁共振成像表现为T1加权像上与正常灰质相似，T2加权像上略呈高信号，钆注射后无强化，提示诊断。下丘脑错构瘤是先天性畸形，由比例与正常组织相似的紊乱成熟神经元成分组成[1]。它们在1至7岁的婴儿中有临床证据[1-5]。本报告描述了一例在新生儿期经组织学证实的巨大下丘脑错构瘤。磁共振成像（MRI）有助于将这种先天性非进展性畸形与更具侵袭性的新生儿肿瘤区分开来。
