Lee Woo Jin, Lee Ga Young, Won Kwang Hee, Won Chong Hyun, Lee Mi Woo, Choi Jee Ho, Chang Sung Eun
Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Indian J Dermatol Venereol Leprol. 2014 Jul-Aug;80(4):313-9. doi: 10.4103/0378-6323.136893.
The clinical and histopathological characteristics of acquired bilateral nevus of Ota-like macules in men are poorly documented due to its rarity.
To compare the clinical and histopathological characteristics of acquired bilateral nevus of Ota-like macules in men with the condition in women.
We studied 11 men and 62 women, all with a clinical diagnosis of acquired bilateral nevus of Ota-like macules. Biopsies were taken from 5 men and 10 women and their clinical and histopathological features were compared.
The most frequently affected site in men was the forehead [8 (73%) out of 11 patients]. Lesions on the forehead were more common in men than women (P = 0.001). In contrast to women, there was no apparent tendency of the lesions to become more blue with age in men. Concurrent melasma was observed in 14 (23%) out of 62 women, but not in men. Extra-facial acquired dermal melanocytosis was noted in 2 (18%) out of 11 men and in none of the 62 women.
Significant differences were noted between men and women in the appearance of concurrent pigmentary lesions and the distribution of lesions. Extra-facial acquired dermal melanocytosis was noted in men.
由于后天性双侧太田痣样斑在男性中较为罕见,其临床和组织病理学特征的文献记载较少。
比较后天性双侧太田痣样斑在男性和女性中的临床及组织病理学特征。
我们研究了11名男性和62名女性,所有患者临床诊断均为后天性双侧太田痣样斑。对5名男性和10名女性进行活检,并比较他们的临床和组织病理学特征。
男性中最常受累的部位是前额[11例患者中有8例(73%)]。前额的损害在男性中比女性更常见(P = 0.001)。与女性不同,男性的损害没有随年龄增长而明显变蓝的趋势。62名女性中有14名(23%)并发黄褐斑,而男性中未观察到。11名男性中有2名(18%)出现面部以外的后天性皮肤黑素细胞增多症,62名女性中均未出现。
在并发色素沉着性损害的外观和损害分布方面,男性和女性之间存在显著差异。男性出现了面部以外的后天性皮肤黑素细胞增多症。