Jairath Vijayeeta, Sehrawat Manu, Jindal Nidhi, Jain V K, Aggarwal Parul
Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India.
Indian J Dermatol Venereol Leprol. 2014 Jul-Aug;80(4):320-3. doi: 10.4103/0378-6323.136894.
Lyme disease is a multiorgan animal-borne disease caused by the spirochete Borrelia burgdorferi. This case series highlights its presence in Haryana, a nonendemic zone. The first case was a 27-year-old housewife who presented with an annular erythematous patch with a central papule following an insect bite on the left upper arm. The second case was a 32-year-old farmer who gave a history of insect bite on the right arm followed by the development of an erythematous patch with a central blister. The third case, a 17-year-old boy presented with a history of tick bite over right thigh and a typical bull's eye lesion with central ulceration. These cases were managed with oral doxycycline 100 mg twice daily for 14 days. The fourth case was a 7-year-old boy with typical erythema migrans on the right check and neck while the fifth case, a 30-year-old housewife, presented with an erythematous patch with a central papule on the right buttock. These patients were treated with oral amoxycillin 25 mg/kg, thrice daily for 14 days. All patients showed IgM antibodies to B. burgdorferi. Treatment led to clearance of lesions in all the patients. Lyme borreliosis was diagnosed in these patients based on the history of established exposure to tick bites, presence of classic signs and symptoms, serology and the response to treatment.
莱姆病是一种由伯氏疏螺旋体引起的多器官动物传播疾病。本病例系列突出了其在非流行区哈里亚纳邦的存在情况。首例病例是一名27岁的家庭主妇，左上臂被昆虫叮咬后出现一个带有中央丘疹的环状红斑斑块。第二例病例是一名32岁的农民，其右臂有昆虫叮咬史，随后出现一个带有中央水疱的红斑斑块。第三例病例，一名17岁男孩，右大腿有蜱叮咬史，并出现一个带有中央溃疡的典型靶心样损害。这些病例采用口服多西环素100毫克，每日两次，共14天进行治疗。第四例病例是一名7岁男孩，右侧脸颊和颈部有典型的游走性红斑，而第五例病例，一名30岁的家庭主妇，右侧臀部出现一个带有中央丘疹的红斑斑块。这些患者采用口服阿莫西林25毫克/千克，每日三次，共14天进行治疗。所有患者均显示出针对伯氏疏螺旋体的IgM抗体。治疗使所有患者的皮损消退。根据有明确的蜱叮咬暴露史、典型体征和症状、血清学检查以及对治疗的反应，对这些患者诊断为莱姆疏螺旋体病。
