Salih Ağırtaş M, Karataş Ceyhun, Özdemir Sadin
Department of Chemistry, Faculty of Science, Yüzüncü Yıl University, 65080 Van, Turkey.
Department of Chemistry, Faculty of Science, Yüzüncü Yıl University, 65080 Van, Turkey.
Spectrochim Acta A Mol Biomol Spectrosc. 2015 Jan 25;135:20-4. doi: 10.1016/j.saa.2014.06.139. Epub 2014 Jul 8.
The synthesis, characterization, spectral, antioxidant and antibacterial properties of dimethyl 5-(phenoxy)-isophthalate substituted Zinc, Cobalt, Copper, and Nickel phthalocyanines are reported. The novel compounds have been characterized by using electronic absorption, nuclear magnetic resonance spectroscopy, infrared, elemental analysis and mass spectrometry. The antioxidant and antibacterial activities of newly synthesized phthalocyanines and its starting material are tested. The DPPH free radical scavenging ability of phthalocyanine Co(II) and Zn(II) complexes on DPPH are 44.8% and 40.1% at 100 mg/L concentration, respectively. The phthalocyanine Co(II) and Cu(II) complexes show very strong ferrous ion chelating activity of 91.2% and 89.3% at concentration of 100 mg/L, respectively. Compound 3 displays strong reducing power like α-tocopherol. Antibacterial activities of phthalocyanine Co(II) and Amikacin (30 μg/disk) against Micrococcus luteus (ATCC 9341) are 16 mm in diameter.
报道了5-(苯氧基)间苯二甲酸二甲酯取代的锌、钴、铜和镍酞菁的合成、表征、光谱、抗氧化和抗菌性能。通过电子吸收、核磁共振光谱、红外光谱、元素分析和质谱对这些新型化合物进行了表征。测试了新合成的酞菁及其起始原料的抗氧化和抗菌活性。在100 mg/L浓度下，酞菁钴(II)和锌(II)配合物对DPPH的自由基清除能力分别为44.8%和40.1%。在100 mg/L浓度下，酞菁钴(II)和铜(II)配合物分别表现出91.2%和89.3%的非常强的亚铁离子螯合活性。化合物3表现出与α-生育酚相似的强还原能力。酞菁钴(II)和阿米卡星(30 μg/圆盘)对藤黄微球菌(ATCC 9341)的抗菌活性直径为16 mm。
