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格鲁吉亚国内炭疽芽孢杆菌的系统发育地理学研究显示出种群结构的证据,且与其他区域基因型不同。

Phylogeography of Bacillus anthracis in the country of Georgia shows evidence of population structuring and is dissimilar to other regional genotypes.

作者信息

Khmaladze Ekaterine, Birdsell Dawn N, Naumann Amber A, Hochhalter Christian B, Seymour Meagan L, Nottingham Roxanne, Beckstrom-Sternberg Stephen M, Beckstrom-Sternberg James, Nikolich Mikeljon P, Chanturia Gvantsa, Zhgenti Ekaterine, Zakalashvili Mariam, Malania Lile, Babuadze Giorgi, Tsertsvadze Nikoloz, Abazashvili Natalia, Kekelidze Merab, Tsanava Shota, Imnadze Paata, Ganz Holly H, Getz Wayne M, Pearson Ofori, Gajer Pawel, Eppinger Mark, Ravel Jacques, Wagner David M, Okinaka Richard T, Schupp James M, Keim Paul, Pearson Talima

机构信息

National Center for Disease Control and Public Health, Tbilisi, Georgia; Ivane Javakhishvili Tbilisi State University, Tbilisi, Georgia.

Center for Microbial Genetics and Genomics, Northern Arizona University, Flagstaff, Arizona, United States of America.

出版信息

PLoS One. 2014 Jul 21;9(7):e102651. doi: 10.1371/journal.pone.0102651. eCollection 2014.

Abstract

Sequence analyses and subtyping of Bacillus anthracis strains from Georgia reveal a single distinct lineage (Aust94) that is ecologically established. Phylogeographic analysis and comparisons to a global collection reveals a clade that is mostly restricted to Georgia. Within this clade, many groups are found around the country, however at least one subclade is only found in the eastern part. This pattern suggests that dispersal into and out of Georgia has been rare and despite historical dispersion within the country, for at least for one lineage, current spread is limited.

摘要

对来自格鲁吉亚的炭疽芽孢杆菌菌株进行的序列分析和亚型分析显示,存在一个生态上已确立的独特谱系(Aust94)。系统地理学分析以及与全球菌株库的比较显示,有一个进化枝主要局限于格鲁吉亚。在这个进化枝内,在该国各地发现了许多群体,但至少有一个亚进化枝仅在东部地区被发现。这种模式表明,进出格鲁吉亚的传播很少见,而且尽管在该国境内有过历史传播,但至少对于一个谱系来说,目前的传播是有限的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e32b/4105404/f50edefe55d9/pone.0102651.g001.jpg

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