Ohtsu R, Fukuyoshi S, Takahashi K
Kansenshogaku Zasshi. 1989 Aug;63(8):816-21. doi: 10.11150/kansenshogakuzasshi1970.63.816.
The existence of virus in fecal specimens was investigated by electron microscopy in five outbreaks of nonbacterial acute gastroenteritis. Small round viruses (SRV) were found in all outbreaks. The negatively stained particles were about 30-35 nm in diameter and with ragged edges. Morphological characteristics resembled each other. Immune electron microscopical examination revealed large aggregates of SRV particles and antibody in convalescent sera from patients of all outbreaks. Furthermore, the second outbreak caused by oysters contaminated with SRV seemed to be associated with the Hawaii agent.
通过电子显微镜对五起非细菌性急性肠胃炎疫情中的粪便标本进行病毒检测。在所有疫情中均发现了小圆病毒（SRV）。经负染的病毒颗粒直径约为30 - 35纳米，边缘参差不齐。形态特征相似。免疫电镜检查显示，所有疫情患者恢复期血清中的SRV颗粒和抗体大量聚集。此外，由受SRV污染的牡蛎引发的第二起疫情似乎与夏威夷病原体有关。
