• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Carbohydrate-mediated modulation of NK cell receptor function: structural and functional influences of heparan sulfate moieties expressed on NK cell surface.

作者信息

Brusilovsky Michael, Radinsky Olga, Yossef Rami, Campbell Kerry S, Porgador Angel

机构信息

The Shraga Segal Department of Microbiology, Immunology and Genetics, Ben-Gurion University of the Negev , Beer-Sheva , Israel.

The Research Institute of Fox Chase Cancer Center , Philadelphia, PA , USA.

出版信息

Front Oncol. 2014 Jul 16;4:185. doi: 10.3389/fonc.2014.00185. eCollection 2014.

DOI:10.3389/fonc.2014.00185
PMID:25077071
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4100077/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af63/4100077/65f5eb34b2fb/fonc-04-00185-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af63/4100077/65f5eb34b2fb/fonc-04-00185-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af63/4100077/65f5eb34b2fb/fonc-04-00185-g001.jpg

相似文献

1
Carbohydrate-mediated modulation of NK cell receptor function: structural and functional influences of heparan sulfate moieties expressed on NK cell surface.碳水化合物介导的自然杀伤细胞受体功能调节:自然杀伤细胞表面表达的硫酸乙酰肝素部分的结构和功能影响
Front Oncol. 2014 Jul 16;4:185. doi: 10.3389/fonc.2014.00185. eCollection 2014.
2
Membrane-associated heparan sulfate proteoglycans are involved in the recognition of cellular targets by NKp30 and NKp46.膜相关硫酸乙酰肝素蛋白聚糖参与NKp30和NKp46对细胞靶标的识别。
J Immunol. 2004 Aug 15;173(4):2392-401. doi: 10.4049/jimmunol.173.4.2392.
3
Natural cytotoxicity receptors NKp30, NKp44 and NKp46 bind to different heparan sulfate/heparin sequences.天然细胞毒性受体NKp30、NKp44和NKp46与不同的硫酸乙酰肝素/肝素序列结合。
J Proteome Res. 2009 Feb;8(2):712-20. doi: 10.1021/pr800747c.
4
Regulation of natural cytotoxicity receptors by heparan sulfate proteoglycans in -cis: A lesson from NKp44.硫酸乙酰肝素蛋白聚糖对自然细胞毒性受体的顺式调节:来自NKp44的启示。
Eur J Immunol. 2015 Apr;45(4):1180-91. doi: 10.1002/eji.201445177. Epub 2015 Jan 21.
5
Characterization of the heparin/heparan sulfate binding site of the natural cytotoxicity receptor NKp46.天然细胞毒性受体NKp46的肝素/硫酸乙酰肝素结合位点的表征
Biochemistry. 2005 Nov 8;44(44):14477-85. doi: 10.1021/bi051241s.
6
Effects of prolactin and cortisol on natural killer (NK) cell surface expression and function of human natural cytotoxicity receptors (NKp46, NKp44 and NKp30).催乳素和皮质醇对人自然杀伤细胞(NK)表面表达及自然细胞毒性受体(NKp46、NKp44和NKp30)功能的影响。
Clin Exp Immunol. 2005 Feb;139(2):287-96. doi: 10.1111/j.1365-2249.2004.02686.x.
7
Natural cytotoxicity receptors: pattern recognition and involvement of carbohydrates.自然细胞毒性受体:模式识别与碳水化合物的参与
ScientificWorldJournal. 2005 Feb 23;5:151-4. doi: 10.1100/tsw.2005.22.
8
Altered glycosylation of recombinant NKp30 hampers binding to heparan sulfate: a lesson for the use of recombinant immunoreceptors as an immunological tool.重组NKp30糖基化改变阻碍其与硫酸乙酰肝素的结合:关于将重组免疫受体用作免疫工具的教训
Glycobiology. 2008 Jan;18(1):28-41. doi: 10.1093/glycob/cwm125. Epub 2007 Nov 15.
9
Regulation of the Functions of Natural Cytotoxicity Receptors by Interactions with Diverse Ligands and Alterations in Splice Variant Expression.通过与多种配体相互作用及剪接变体表达改变对自然细胞毒性受体功能的调节
Front Immunol. 2017 Mar 30;8:369. doi: 10.3389/fimmu.2017.00369. eCollection 2017.
10
Influence of in vitro IL-2 or IL-15 alone or in combination with Hsp-70-derived 14-mer peptide (TKD) on the expression of NK cell activatory and inhibitory receptors.体外单独使用白细胞介素-2(IL-2)或白细胞介素-15(IL-15)或联合热休克蛋白-70 衍生的 14 肽(TKD)对 NK 细胞激活性和抑制性受体表达的影响。
Mediators Inflamm. 2013;2013:405295. doi: 10.1155/2013/405295. Epub 2013 Feb 17.

引用本文的文献

1
NK cell activity in the tumor microenvironment.肿瘤微环境中的自然杀伤细胞活性。
Front Cell Dev Biol. 2025 May 30;13:1609479. doi: 10.3389/fcell.2025.1609479. eCollection 2025.
2
Non-viral approaches in CAR-NK cell engineering: connecting natural killer cell biology and gene delivery.非病毒方法在 CAR-NK 细胞工程中的应用:连接自然杀伤细胞生物学和基因传递。
J Nanobiotechnology. 2024 Sep 10;22(1):552. doi: 10.1186/s12951-024-02746-4.
3
NKp30 - A prospective target for new cancer immunotherapy strategies.NKp30 - 一种新的癌症免疫治疗策略的前瞻性靶标。

本文引用的文献

1
Natural cytotoxicity receptors and their ligands.自然细胞毒性受体及其配体。
Immunol Cell Biol. 2014 Mar;92(3):221-9. doi: 10.1038/icb.2013.98. Epub 2013 Dec 24.
2
Genome-wide siRNA screen reveals a new cellular partner of NK cell receptor KIR2DL4: heparan sulfate directly modulates KIR2DL4-mediated responses.全基因组 siRNA 筛选揭示 NK 细胞受体 KIR2DL4 的新细胞伙伴:硫酸乙酰肝素直接调节 KIR2DL4 介导的反应。
J Immunol. 2013 Nov 15;191(10):5256-67. doi: 10.4049/jimmunol.1302079. Epub 2013 Oct 14.
3
Induction of B7-H6, a ligand for the natural killer cell-activating receptor NKp30, in inflammatory conditions.
Br J Pharmacol. 2020 Oct;177(20):4563-4580. doi: 10.1111/bph.15222. Epub 2020 Aug 26.
4
An Historical Overview: The Discovery of How NK Cells Can Kill Enemies, Recruit Defense Troops, and More.历史概述:NK 细胞如何杀死敌人、招募防御部队等的发现过程。
Front Immunol. 2019 Jun 19;10:1415. doi: 10.3389/fimmu.2019.01415. eCollection 2019.
5
BPTF inhibits NK cell activity and the abundance of natural cytotoxicity receptor co-ligands.BPTF抑制自然杀伤细胞活性以及自然细胞毒性受体共配体的丰度。
Oncotarget. 2017 May 12;8(38):64344-64357. doi: 10.18632/oncotarget.17834. eCollection 2017 Sep 8.
6
The regulation of ovary and conceptus on the uterine natural killer cells during early pregnancy.妊娠早期卵巢和孕体对子宫自然杀伤细胞的调节作用。
Reprod Biol Endocrinol. 2017 Sep 6;15(1):73. doi: 10.1186/s12958-017-0290-1.
7
Decreased Human Leukocyte Antigen-G Expression by miR-133a Contributes to Impairment of Proinvasion and Proangiogenesis Functions of Decidual NK Cells.miR-133a降低人白细胞抗原-G表达导致蜕膜自然杀伤细胞促侵袭和促血管生成功能受损。
Front Immunol. 2017 Jun 28;8:741. doi: 10.3389/fimmu.2017.00741. eCollection 2017.
8
KIR, LILRB and their Ligands' Genes as Potential Biomarkers in Recurrent Implantation Failure.KIR、LILRB 及其配体基因作为复发性植入失败的潜在生物标志物。
Arch Immunol Ther Exp (Warsz). 2017 Oct;65(5):391-399. doi: 10.1007/s00005-017-0474-6. Epub 2017 May 18.
9
Regulation of the Functions of Natural Cytotoxicity Receptors by Interactions with Diverse Ligands and Alterations in Splice Variant Expression.通过与多种配体相互作用及剪接变体表达改变对自然细胞毒性受体功能的调节
Front Immunol. 2017 Mar 30;8:369. doi: 10.3389/fimmu.2017.00369. eCollection 2017.
10
Possible Role of HLA-G, LILRB1 and KIR2DL4 Gene Polymorphisms in Spontaneous Miscarriage.HLA - G、LILRB1和KIR2DL4基因多态性在自然流产中的可能作用
Arch Immunol Ther Exp (Warsz). 2016 Dec;64(6):505-514. doi: 10.1007/s00005-016-0389-7. Epub 2016 Mar 14.
诱导共刺激分子 B7-H6 的表达,B7-H6 是自然杀伤细胞激活受体 NKp30 的配体,在炎症条件下。
Blood. 2013 Jul 18;122(3):394-404. doi: 10.1182/blood-2013-01-481705. Epub 2013 May 17.
4
Activating natural cytotoxicity receptors of natural killer cells in cancer and infection.激活自然杀伤细胞自然细胞毒性受体在癌症和感染中的作用。
Trends Immunol. 2013 Apr;34(4):182-91. doi: 10.1016/j.it.2013.01.003. Epub 2013 Feb 13.
5
The proteoglycan repertoire of lymphoid cells.淋巴细胞的蛋白聚糖组。
Glycoconj J. 2012 Oct;29(7):513-23. doi: 10.1007/s10719-012-9427-9. Epub 2012 Jul 10.
6
[Glycan ligand specificity of killer lectin receptors].
Yakugaku Zasshi. 2012;132(6):705-12. doi: 10.1248/yakushi.132.705.
7
Syndecan 4 regulates FGFR1 signaling in endothelial cells by directing macropinocytosis.Syndecan 4 通过指导巨胞饮作用调节内皮细胞中的 FGFR1 信号。
Sci Signal. 2012 May 8;5(223):ra36. doi: 10.1126/scisignal.2002495.
8
Human NK cell recognition of target cells in the prism of natural cytotoxicity receptors and their ligands.自然细胞毒性受体及其配体视角下的人自然杀伤细胞对靶细胞的识别。
J Immunotoxicol. 2012 Jul-Sep;9(3):267-74. doi: 10.3109/1547691X.2012.675366. Epub 2012 Apr 23.
9
Proliferating cell nuclear antigen is a novel inhibitory ligand for the natural cytotoxicity receptor NKp44.增殖细胞核抗原是自然细胞毒性受体 NKp44 的新型抑制性配体。
J Immunol. 2011 Dec 1;187(11):5693-702. doi: 10.4049/jimmunol.1102267. Epub 2011 Oct 21.
10
Binding affinities of NKG2D and CD94 to sialyl Lewis X-expressing N-glycans and heparin.NKG2D 和 CD94 与表达唾液酸化 Lewis X 的 N-糖链和肝素的结合亲和力。
Biol Pharm Bull. 2011;34(1):8-12. doi: 10.1248/bpb.34.8.