Department of Orthopaedic and Trauma Surgery, Campus Bio-Medico University of Rome, Via Álvaro del Portillo 200, 00128 Rome, Italy ; Centro Integrato di Ricerca (CIR), Università Campus Bio-Medico di Roma, Via Álvaro del Portillo 21, 00128 Rome, Italy.
University CEU San Pablo, 28003 Madrid, Spain.
Stem Cells Int. 2012;2012:420346. doi: 10.1155/2012/420346. Epub 2011 Oct 26.
Meniscal tears are the most common knee injuries and have a poor ability of healing. In the last few decades, several techniques have been increasingly used to optimize meniscal healing. Current research efforts of tissue engineering try to combine cell-based therapy, growth factors, gene therapy, and reabsorbable scaffolds to promote healing of meniscal defects. Preliminary studies did not allow to draw definitive conclusions on the use of these techniques for routine management of meniscal lesions. We performed a review of the available literature on current techniques of tissue engineering for the management of meniscal tears.
半月板撕裂是最常见的膝关节损伤，其愈合能力较差。在过去几十年中，已经有几种技术被越来越多地用于优化半月板愈合。目前组织工程学的研究努力旨在结合基于细胞的治疗、生长因子、基因治疗和可吸收支架来促进半月板缺损的愈合。初步研究尚不能对这些技术在半月板损伤常规治疗中的应用得出明确结论。我们对当前用于治疗半月板撕裂的组织工程技术的现有文献进行了回顾。
