咖啡因会改变2型糖尿病患者在长时间低强度运动期间的血糖可用性。
Caffeine modifies blood glucose availability during prolonged low-intensity exercise in individuals with type-2 diabetes.
作者信息
da Silva Luiz Augusto, de Freitas Leandro, Medeiros Thiago Emannuel, Osiecki Raul, Garcia Michel Renan, Snak André Luiz, Malfatti Carlos Ricardo Maneck
机构信息
Midwest State University of Parana, Pharmaceutical Science Postgraduate Program, Guarapuava, PR, Brazil.
State University of Santa Catarina, Physical Education Postgraduate Program, Florianópolis, SC, Brazil.
出版信息
Colomb Med (Cali). 2014 Jun 30;45(2):72-6. eCollection 2014 Apr-Jun.
OBJECTIVE
The study investigated the effect of supplementation with maltodextrin (CHO) alone or associated to caffeine during exercise in T2DM subjects.
METHODS
Pilot study, using eight subjects with T2DM, aged 55±10 years, received CHO (1 g/kg) or caffeine (1.5 mg/kg) alone or associated before exercise protocol. The exercise was executed at 40% heart rate (HR) reserve for 40 min, with 10-min recovery. Blood pressure (BP) and perceived exertion scale (Borg) were checked every 2 min. Blood glucose (BG) was checked every 10 min. For statistical analysis, ANOVA test was used and the value was considered statistically significant at p <0.05.
RESULTS
The results showed that BP and HR did not change significantly among all treatments. Caffeine promoted a significant reduction in BG of 75 mg/dL (65%, p <0.05) during 40 min of exercise protocol compared to all groups.
CONCLUSION
Supplementation with 1.5 mg/kg of caffeine reduces BG concentration during prolonged exercise in T2DM patients.
目的
本研究调查了在2型糖尿病受试者运动期间单独补充麦芽糊精（碳水化合物）或与咖啡因联合补充的效果。
方法
进行了一项初步研究，选取8名年龄在55±10岁的2型糖尿病受试者，在运动方案前单独或联合给予碳水化合物（1克/千克）或咖啡因（1.5毫克/千克）。运动以心率储备的40%进行40分钟，随后恢复10分钟。每2分钟检查一次血压（BP）和自觉用力程度量表（Borg）。每10分钟检查一次血糖（BG）。进行统计分析时使用方差分析测试，p<0.05时该值被认为具有统计学意义。
结果
结果表明，所有治疗组之间血压和心率均无显著变化。与所有组相比，在40分钟的运动方案期间，咖啡因使血糖显著降低75毫克/分升（65%，p<0.05）。
结论
在2型糖尿病患者长时间运动期间，补充1.5毫克/千克咖啡因可降低血糖浓度。
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