Yamashita K, Kataoka Y, Shibata K, Ozaki T, Miyazaki A, Kagoshima M, Ueki S
Department of Pharmacology 2, Nagasaki University School of Medicine, Japan.
Neurosci Lett. 1989 Sep 25;104(1-2):195-200. doi: 10.1016/0304-3940(89)90354-6.
The present study was designed to clarify neural circuits involved in the mediation of behavioral suppression using the Vogel type conflict procedure in rats. Among the brain nuclei inclusive of neuroanatomical substrates of behavioral suppression, lesioning of the central amygdala, mammillary body or frontal cortex led to a significant increase in the punished drinking responses. Lesion of the septum also tended to increase these responses. These results show the key role of these brain areas in mediation of behavioral suppression such as conflict behavior.
本研究旨在利用大鼠的Vogel型冲突程序阐明参与行为抑制调节的神经回路。在包括行为抑制的神经解剖学基础的脑核中，中央杏仁核、乳头体或额叶皮质的损伤导致受罚饮水反应显著增加。隔膜损伤也倾向于增加这些反应。这些结果表明这些脑区在诸如冲突行为等行为抑制调节中起关键作用。
