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脊髓损伤患者膀胱颈/外括约肌重复切开术的长期疗效

Long-term efficacy of repeat incisions of bladder neck/external sphincter in patients with spinal cord injury.

作者信息

Vainrib Michael, Reyblat Polina, Ginsberg David A

机构信息

Department of Urology, University of Southern California, Los Angeles, CA; Department of Urology, Meir Medical Center, Kfar Saba, Israel.

Urology Service, Rancho Los Amigos National Rehabilitation Center, Downey, CA; Department of Urology, Kaiser Permanente Los Angeles Medical Center, Los Angeles, CA.

出版信息

Urology. 2014 Oct;84(4):940-5. doi: 10.1016/j.urology.2014.06.009. Epub 2014 Aug 5.

DOI:10.1016/j.urology.2014.06.009
PMID:25102789
Abstract

OBJECTIVE

To evaluate the efficacy of repeat bladder neck incision (BNI), with or without external sphincterotomy (ES). BNI/ES has been commonly used for management of neurogenic bladder in spinal cord injury (SCI) patients.

METHODS

This was a retrospective review of institutional review board-approved SCI database.

RESULTS

A total of 97 patients underwent BNI/ES over a period of 40 years. During the period reviewed, a solitary redo BNI/ES was done in 46 patients, a second redo BNI/ES was done in 23 patients, and a third redo BNI/ES was done in 7 patients with success rates of 50%, 68.2%, and 85.7%, respectively. The most common indications for surgery failure and need for repeat surgery were elevated residual for the first repeat BNI/ES, recurrent urinary tract infections for the second, and elevated residual for the third repeat BNI/ES. All patients had a normal serum creatinine level at the end of the follow-up. Mean elapsed follow-up after the last redo BNI/ES was 119 months (range, 6-408 months) for all patients evaluated. Mean durability of successful redo BNI/ES was 109.1 months, which was significantly longer than mean durability of failed redo BNI/ES at 69.4 months (P <.05).

CONCLUSION

SCI patients undergoing BNI/ES may require repeat BNI/ES to optimize lower urinary tract management. The success rate ranges from 50% to 85.7% after 3 repeat BNI/ES procedures with acceptable long-term durability and low perioperative complication rates.

摘要

目的

评估重复膀胱颈切开术(BNI)联合或不联合外括约肌切开术(ES)的疗效。BNI/ES已常用于脊髓损伤(SCI)患者神经源性膀胱的治疗。

方法

这是一项对机构审查委员会批准的SCI数据库进行的回顾性研究。

结果

40年间共有97例患者接受了BNI/ES治疗。在研究期间,46例患者进行了单次重复BNI/ES,23例患者进行了第二次重复BNI/ES,7例患者进行了第三次重复BNI/ES,成功率分别为50%、68.2%和85.7%。手术失败及需要再次手术的最常见原因,首次重复BNI/ES是残余尿量增加,第二次是反复尿路感染,第三次是残余尿量增加。所有患者在随访结束时血清肌酐水平均正常。对所有评估患者而言,末次重复BNI/ES后的平均随访时间为119个月(范围6 - 408个月)。成功的重复BNI/ES的平均持续时间为109.1个月,显著长于失败的重复BNI/ES的平均持续时间69.4个月(P <.05)。

结论

接受BNI/ES治疗的SCI患者可能需要重复BNI/ES以优化下尿路管理。在进行3次重复BNI/ES手术后,成功率为50%至85.7%,具有可接受的长期持续性和较低的围手术期并发症发生率。

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