Stinco Giuseppe, Trevisan Giusto, Piccirillo Fabio, Pezzetta Serena, Errichetti Enzo, di Meo Nicola, Valent Francesca, Patrone Pasquale
Giuseppe Stinco, MD Institute of Dermatology University of Udine Ospedale "San Michele", Piazza Rodolone 1, 33013-Gemona del Friuli, Udine, Italy;
Acta Dermatovenerol Croat. 2014;22(2):122-8.
In the past, several textbooks defined psoriasis as a non-pruritic dermatosis, but the most recent data in the literature emphasizes the high frequency of pruritus in psoriasis and its impact on the quality of life of patients with psoriasis. Aim of this study was to explore the sensory and affective dimensions of pruritus as well as to assess the impact of itch on quality of life and to evaluate the influence of lifestyles, habits, and various anti-pruritic therapies on pruritus in a large group of psoriatic subjects. The structured Yosipovitch itch questionnaire was given to 240 psoriatic patients. 230 patients returned a complete and detailed questionnaire. Pruritus was referred to by 80% of the patients. Psoriasis area and severity index (PASI) was significantly higher in itching-patients (P=0.04). In half of the patients, itching appeared daily, particularly in the evening. Significant aggravating factors of pruritus were stress, skin dryness, hot water, sweating, elevated ambient temperature, exercise, abundant meals, bad moods, lying position, and contact with clothes. Cold water is the only factor that showed to significantly relieve the pruritus. Anti-pruritic therapies had limited effect. Pruritus is a common, bothersome, and poorly responsive symptom in patients with psoriasis.
过去，几本教科书将银屑病定义为一种无瘙痒的皮肤病，但文献中的最新数据强调了银屑病中瘙痒的高发生率及其对银屑病患者生活质量的影响。本研究的目的是探讨瘙痒的感觉和情感维度，评估瘙痒对生活质量的影响，并评估生活方式、习惯和各种止痒疗法对一大群银屑病患者瘙痒的影响。向240名银屑病患者发放了结构化的约西波维奇瘙痒问卷。230名患者返回了完整详细的问卷。80%的患者提到有瘙痒。瘙痒患者的银屑病面积和严重程度指数（PASI）显著更高（P=0.04）。一半的患者每天都会出现瘙痒，尤其是在晚上。瘙痒的显著加重因素包括压力、皮肤干燥、热水、出汗、环境温度升高、运动、饮食丰盛、情绪不佳、躺卧姿势以及与衣物接触。冷水是唯一显示能显著缓解瘙痒的因素。止痒疗法效果有限。瘙痒是银屑病患者常见、困扰且反应不佳的症状。
