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脊髓硬脊膜动静脉瘘的治疗。12例报告并文献复习。

Management of spinal dural arterio-venous fistulas. Report of 12 cases and review of literature.

作者信息

Rashad Sherif, Abdel-Bary Mohamed, Aziz Waseem, Hassan Tamer

机构信息

Department of Neurosurgery, Alexandria University School of Medicine, Alexandria, Egypt.

Department of Neurosurgery, Alexandria University School of Medicine, Alexandria, Egypt.

出版信息

Clin Neurol Neurosurg. 2014 Oct;125:81-6. doi: 10.1016/j.clineuro.2014.07.028. Epub 2014 Jul 27.

Abstract

INTRODUCTION

Spinal cord arteriovenous malformations and fistulae are rare vascular lesions than can lead to myelopathy that is at many instances overlooked during diagnosing the cause of progressive myelopathy and weakness. Treatment options involve either endovascular embolization, surgical disconnection or a combination of both. This study aims to evaluate various treatment methods for sDAVFs and the outcome of these methods.

METHODS

This study involved 12 patients suffering from symptoms attributed to spinal dural arteriovenous fistulas; 11 were male and one was a female patient, with ages ranging between 50 years and 71 years. All patients presented with progressive spastic paraparesis of varying grades, and 6 had sphincter disturbances prior to treatment. Patients were evaluated by Aminoff-Logue motor disability scale.

RESULTS

Three were managed by endovascular embolization and 9 by surgical disconnection. Three patients showed full recovery after treatment, 7 patients showed no change in their neurological status following treatment, and 2 patients showed partial recovery after treatment.

CONCLUSION

Spinal AVF is a rare curable cause of spinal myelopathy if managed promptly. Good angiographic studies prior to treatment decision are a must, in order to plan the best approach according to the angioarchitecture of the fistula whether it will allow endovascular embolization or will surgery be more feasible.

摘要

引言

脊髓动静脉畸形和瘘是罕见的血管病变,可导致脊髓病,在诊断进行性脊髓病和肌无力的病因时,很多情况下会被忽视。治疗选择包括血管内栓塞、手术切断或两者结合。本研究旨在评估脊髓硬脊膜动静脉瘘(sDAVF)的各种治疗方法及其疗效。

方法

本研究纳入12例因脊髓硬脊膜动静脉瘘出现症状的患者;11例为男性,1例为女性,年龄在50岁至71岁之间。所有患者均表现为不同程度的进行性痉挛性截瘫,6例在治疗前有括约肌功能障碍。采用阿明诺夫-洛格运动残疾量表对患者进行评估。

结果

3例采用血管内栓塞治疗,9例采用手术切断治疗。3例患者治疗后完全恢复,7例患者治疗后神经状态无变化,2例患者治疗后部分恢复。

结论

脊髓动静脉瘘若能及时治疗,是脊髓病一种罕见的可治愈病因。在决定治疗方案前进行良好的血管造影检查是必要的,以便根据瘘的血管结构规划最佳治疗方法,判断是否适合血管内栓塞或手术更为可行。

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