Kocabicak Ersoy, Terzi Murat, Akpinar Kursad, Paksoy Kemal, Cebeci Ibrahim, Iyigun Omer
Department of Neurosurgery, Ondokuz Mayis University, Faculty of Medicine, 55200 Samsun, Turkey ; Departments of Neurosurgery and Neuroscience, Maastricht University Medical Center, P. Debyelaan 25, 6202 AZ Maastricht, The Netherlands.
Department of Neurology, Ondokuz Mayis University, Faculty of Medicine, 55200 Samsun, Turkey.
Behav Neurol. 2014;2014:245358. doi: 10.1155/2014/245358. Epub 2014 Jul 8.
To investigate the frequency of restless leg syndrome (RLS), sleep quality impairment, depression, fatigue, and sleep behavior disorder and to determine the effects of surgery on these parameters in radiculopathy patients resistant to conservative treatment.
The present study included 66 lumbar radiculopathy patients, who were resistant to conservative treatment and had indication of surgery. Five different questionnaires were performed to assess depression (the Beck Depression Inventory (BDI)), sleep quality (the Pittsburgh Sleep Quality Index (PSQI)), fatigue (the Fatigue Severity Scale (FSS)), and presence of RLS and rapid eye movement sleep behavior disorder (RBD). The same questionnaires were also performed on a control group (n = 61).
Of the radiculopathy patients, 68.1% had RLS and 92.4% had fatigue. Of the controls, 16.4% had RLS and 59% had fatigue. RBD was present in 8 (12.1%) patients and 3 (4.9%) controls. The PSQI revealed that sleep quality was impaired in 46 (69.7%) patients and 35 (57.4%) controls (P > 0.05). The number of individuals having substantial depression according to the BDI was significantly higher in the patients than in the controls.
There was a significant increase in the frequency of RLS, which was significantly decreased in the postoperative period in the radiculopathy patients.
调查不宁腿综合征（RLS）、睡眠质量受损、抑郁、疲劳及睡眠行为障碍的发生率，并确定手术对保守治疗无效的神经根病患者上述指标的影响。
本研究纳入66例对保守治疗无效且有手术指征的腰椎神经根病患者。采用5种不同问卷评估抑郁（贝克抑郁量表（BDI））、睡眠质量（匹兹堡睡眠质量指数（PSQI））、疲劳（疲劳严重程度量表（FSS））以及RLS和快速眼动睡眠行为障碍（RBD）的存在情况。对对照组（n = 61）也采用相同问卷进行评估。
神经根病患者中，68.1%有RLS，92.4%有疲劳。对照组中，16.4%有RLS，59%有疲劳。8例（12.1%）患者和3例（4.9%）对照有RBD。PSQI显示，46例（69.7%）患者和35例（57.4%）对照的睡眠质量受损（P > 0.05）。根据BDI，患者中存在明显抑郁的人数显著高于对照组。
神经根病患者中RLS的发生率显著增加，术后该发生率显著降低。
