Incebiyik A, Camuzcuoglu A, Hilali N Gul, Ulas T, Vural M, Camuzcuoglu H, Aksoy N
Department of Obstetrics and Gynecology, Faculty of Medicine, Harran University , Sanliurfa , Turkey.
J Obstet Gynaecol. 2015 Feb;35(2):188-92. doi: 10.3109/01443615.2014.948399. Epub 2014 Aug 11.
The aim of this study was to investigate whether there is a relationship between premenstrual syndrome and oxidative stress, visfatin and apelin. The study included 40 women with premenstrual syndrome and 40 healthy women. In all subjects, serum visfatin, apelin and oxidative stress parameters were studied in venous blood samples. The oxidative stress parameters were higher in the premenstrual syndrome group than among the controls, but this difference did not reach statistical significance (p > 0.05). It was found that total antioxidant capacity was similar in both groups. For the insulin-serotonin cycle markers, no significant difference was found between groups in terms of visfatin level (p = 0.893), although apelin was found to be significantly higher in the premenstrual syndrome group when compared with the controls (p < 0.001). According to our results, apelin can be used as an ancillary laboratory test in the diagnosis of premenstrual syndrome.
本研究的目的是调查经前综合征与氧化应激、内脂素和脂联素之间是否存在关联。该研究纳入了40名经前综合征女性和40名健康女性。对所有受试者的静脉血样本进行血清内脂素、脂联素和氧化应激参数检测。经前综合征组的氧化应激参数高于对照组，但这种差异未达到统计学显著性（p>0.05）。发现两组的总抗氧化能力相似。对于胰岛素 - 血清素循环标志物，两组在内脂素水平方面未发现显著差异（p = 0.893），尽管与对照组相比，经前综合征组的脂联素水平显著更高（p < 0.001）。根据我们的结果，脂联素可作为经前综合征诊断的辅助实验室检查指标。
