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患有进食障碍的青少年、青年和中年成年人的预后不良和死亡:按评估时的年龄调查风险因素。

Poor outcome and death among youth, young adults, and midlife adults with eating disorders: an investigation of risk factors by age at assessment.

机构信息

Park Nicollet Melrose Center, St. Louis Park, Minnesota; Offices of Diann M Ackard, PhD, LP, LLC, Golden Valley, Minnesota.

出版信息

Int J Eat Disord. 2014 Nov;47(7):825-35. doi: 10.1002/eat.22346. Epub 2014 Aug 11.

Abstract

OBJECTIVE

Eating disorders (EDs) present across a broad age range, yet little is known about the characteristics and outcome of midlife patients compared to younger patients. Among patients seeking ED treatment who were stratified by age at initial assessment (IA), this study aimed to (1) discern sociodemographic and clinical differences, (2) determine outcome rates, and (3) identify predictors of poor outcome including death.

METHOD

Participants [219 females (12 years or older, 94.1% Caucasian) who completed outcome assessment and 31 known decedents] were stratified by age at IA (<18 as youth, 18-39 as young adult, and ≥40 years as midlife adult). Analyses of variance and chi-square tests identified group differences; ordered logistic regression with stepwise selection identified factors predicting outcome.

RESULTS

Midlife adults were more significantly compromised at follow-up compared to youths and young adults, including psychological and physical quality of life, ineffectiveness, interpersonal concerns, and general psychological maladjustment. Midlife adults had the highest rates of poor outcome or death; good outcome was achieved by only 5.9% of midlife adult compared to 14.0% of young adult and 27.5% of youth patients. Older age at IA, alcohol and/or drug misuse, endocrine concerns, and absence of family ED history predicted poor outcome or death.

DISCUSSION

Midlife adults seeking ED treatment have more complex medical and psychological concerns and poorer outcomes than youths and young adults; further exploration is needed to improve treatment outcome. Specialized treatment focusing on quality of life, comorbid medical concerns, interpersonal connection, and emotion regulation is encouraged.

摘要

目的

饮食失调(ED)在广泛的年龄范围内存在,但与年轻患者相比,关于中年患者的特征和结局知之甚少。在根据初始评估(IA)时的年龄分层的寻求 ED 治疗的患者中,本研究旨在:(1)辨别社会人口统计学和临床差异,(2)确定结局率,以及(3)确定不良结局的预测因素,包括死亡。

方法

参与者[219 名女性(12 岁或以上,94.1%为白种人)完成了结局评估,31 名已知死亡者]根据 IA 时的年龄分层(<18 岁为青年,18-39 岁为青年成人,≥40 岁为中年成人)。方差分析和卡方检验确定了组间差异;逐步选择的有序逻辑回归确定了预测结局的因素。

结果

与青年和青年成人相比,中年成人在随访时的情况更差,包括心理和生理生活质量、无效、人际关系问题和一般心理适应不良。中年成人的不良结局或死亡发生率最高;仅有 5.9%的中年成人获得良好结局,而青年成人和青年患者的良好结局率分别为 14.0%和 27.5%。IA 时年龄较大、酒精和/或药物滥用、内分泌问题以及没有家族 ED 病史预测了不良结局或死亡。

讨论

寻求 ED 治疗的中年成人比青年和青年成人具有更复杂的医疗和心理问题,且结局更差;需要进一步探索以改善治疗结局。鼓励提供专门针对生活质量、合并医疗问题、人际关系和情绪调节的治疗。

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