Nissimov Sagee, Jacoby Moshe, Shteinshnaider Miriam, Tzur Irma, Gorelik Oleg
Harefuah. 2014 May;153(5):253-4, 306.
Cutis verticis gyrata (CVG) is a descriptive term for a dermal sign in which deep furrows and convoluted ridges are seen upon the scalp. They are formed due to thickening of the skin folds of the scalp and produce an appearance that resembles the gyri of the brain. The condition is classified primary when the etiology is unknown or neurologically based. CVG will be considered secondary when a definite cause, systemic or localized, is responsible for the sign. We describe a 34 year-old male who was presented with a one-month history of arthralgia in his interphalangeal joints. His physical examination revealed scalp changes compatible with CVG, which appeared 3 years earlier. Following a thorough investigation of the patient, acromegaly was diagnosed. Although CVG is a rare condition, it has been described in patients with acromegaly. The appearance of SVG as an early sign of acromegaly makes this case unique and important. In a patient developing CVG, acromegaly and other treatable disorders should always be excluded.
头皮回状颅皮（CVG）是一种描述性术语，用于指头皮出现深沟和回旋状嵴的皮肤体征。它们是由于头皮皮肤褶皱增厚形成的，外观类似脑回。当病因不明或基于神经学原因时，该病症被分类为原发性。当明确的全身性或局部性病因导致该体征时，CVG将被视为继发性。我们描述了一名34岁男性，他有一个月的指间关节疼痛病史。他的体格检查发现头皮变化符合CVG，这种变化在3年前就已出现。对该患者进行全面检查后，诊断为肢端肥大症。尽管CVG是一种罕见病症，但在肢端肥大症患者中已有相关描述。SVG作为肢端肥大症的早期体征出现，使得该病例独特且重要。在出现CVG的患者中，应始终排除肢端肥大症和其他可治疗的疾病。
