Roque Dario R, Wysham Weiya Z, Soper John T
Clinical Fellow, Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of North Carolina, Chapel Hill, NC.
Professor, Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of North Carolina, Chapel Hill, NC.
Obstet Gynecol Surv. 2014 Jul;69(7):426-41. doi: 10.1097/OGX.0000000000000089.
Surgery has evolved into the standard therapy for nonbulky carcinoma of the cervix. The mainstay of surgical management is radical hysterectomy; however, less radical procedures have a small but important role in the management of cervical tumors.
Our objective was to discuss the literature behind the different procedures utilized in the management of cervical cancer, emphasizing the radical hysterectomy. In addition, we aimed to discuss ongoing trials looking at the utility of less radical surgeries as well as emerging technologies in the management of this disease.
We performed a PubMed literature search for articles in the English language that pertained to the topic of surgical techniques and their outcomes in the treatment of cervical cancer.
The minimally invasive approaches to radical hysterectomy appear to reduce morbidity without affecting oncological outcomes, although further data are needed looking at long-term outcomes with the robotic platform. Trials are currently ongoing looking at the role of less radical surgery for patients with low-risk disease and the feasibility of sentinel lymph node mapping.
Radical hysterectomy with pelvic lymphadenectomy has evolved into the standard therapy for nonbulky disease, and there is a clear advantage in the use of minimally invasive techniques to perform these procedures. However, pending ongoing trials, less radical surgery in patients with low-risk invasive disease as well as sentinel lymph node mapping may emerge as standards of care in selected patients with cervical carcinoma.
手术已发展成为宫颈非大块癌的标准治疗方法。手术治疗的主要手段是根治性子宫切除术;然而,不太激进的手术在宫颈肿瘤的治疗中也发挥着虽小但重要的作用。
我们的目的是讨论宫颈癌治疗中所采用的不同手术方法背后的文献,重点是根治性子宫切除术。此外,我们旨在讨论正在进行的关于不太激进手术的效用以及该疾病治疗中新兴技术的试验。
我们在PubMed上搜索了与宫颈癌治疗中的手术技术及其结果相关的英文文章。
尽管需要更多关于机器人平台长期结果的数据,但根治性子宫切除术的微创方法似乎能降低发病率且不影响肿瘤学结果。目前正在进行试验,研究不太激进的手术对低风险疾病患者的作用以及前哨淋巴结定位的可行性。
根治性子宫切除术加盆腔淋巴结清扫术已发展成为非大块疾病的标准治疗方法,采用微创技术进行这些手术具有明显优势。然而,在正在进行的试验结果出来之前,低风险浸润性疾病患者的不太激进手术以及前哨淋巴结定位可能会成为部分宫颈癌患者的护理标准。