情绪障碍跨诊断治疗统一方案的长期疗效初步调查。
A preliminary investigation of the long-term outcome of the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders.
作者信息
Bullis Jacqueline R, Fortune Meghan R, Farchione Todd J, Barlow David H
机构信息
Boston University, 648 Beacon Street, 6th floor, Boston, MA 02215, USA.
出版信息
Compr Psychiatry. 2014 Nov;55(8):1920-7. doi: 10.1016/j.comppsych.2014.07.016. Epub 2014 Jul 22.
Abstract
OBJECTIVE
The aim of this study is to conduct a preliminary examination of long-term outcomes on a broad range of affective disorder symptoms treated with a newly developed intervention: The Unified Protocol for Transdiagnostic Treatment of Emotional Disorders (UP).
METHOD
Maintenance of treatment gains at long-term follow-up (LTFU) were explored in patients (N=15, mean age=32.27; 60% female) who completed a clinical trial of the UP.
RESULTS
Treatment gains observed at 6-month follow-up (6MFU) on measures of clinical severity, general symptoms of depression and anxiety, and a measure of symptom interference in daily functioning were largely maintained 12months later (at an average of 18months posttreatment), and any significant changes from 6MFU to LTFU reflected small increases in symptoms that remained, on average, in the subclinical range.
CONCLUSIONS
These findings provide the first initial support for the durability of broad treatment gains following transdiagnostic treatment.
摘要
目的
本研究旨在对一种新开发的干预措施——情绪障碍跨诊断治疗统一方案（UP）治疗的广泛情感障碍症状的长期结果进行初步检验。
方法
在完成UP临床试验的患者（N = 15，平均年龄 = 32.27岁；60%为女性）中探讨长期随访（LTFU）时治疗效果的维持情况。
结果
在6个月随访（6MFU）时观察到的临床严重程度、抑郁和焦虑的一般症状以及日常功能中症状干扰指标方面的治疗效果，在12个月后（平均治疗后18个月）基本得以维持，从6MFU到LTFU的任何显著变化都反映出症状有小幅增加，平均仍处于亚临床范围内。
结论
这些发现为跨诊断治疗后广泛治疗效果的持久性提供了首个初步支持。
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