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一项针对儿童情绪障碍跨诊断治疗统一方案的随机对照试验性研究

A Randomized Controlled Pilot Trial of the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children.

作者信息

Kennedy Sarah M, Bilek Emily L, Ehrenreich-May Jill

机构信息

1 University of Miami, Coral Gables, FL, USA.

2 University of Michigan, Ann Arbor, MI, USA.

出版信息

Behav Modif. 2019 May;43(3):330-360. doi: 10.1177/0145445517753940. Epub 2018 Jan 27.

DOI:10.1177/0145445517753940
PMID:29374963
Abstract

The Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children (UP-C) is an intervention for children aged 7 to 13 targeting high negative emotion, emotional reactivity, and emotion regulation deficits common across emotional disorders. Our objective was to collect pilot randomized controlled trial (RCT) data on the efficacy of the UP-C, comparing UP-C with an active, anxiety-focused intervention. Participants were 47 children with at least one primary anxiety disorder; approximately one half had elevated depression symptoms. Participants received either UP-C or the anxiety-focused control treatment. No condition-related differences were found with respect to diagnostic remission and anxiety symptoms. However, differences in favor of UP-C were observed with respect to treatment response at follow-up, depression symptoms, sadness dysregulation, and cognitive reappraisal. Results provide preliminary evidence that the UP-C may be at least as efficacious in treating anxiety as well-supported anxiety-specific treatment protocols and may produce greater gains in certain emotion reactivity and regulation variables.

摘要

儿童情绪障碍跨诊断治疗统一方案(UP-C)是一种针对7至13岁儿童的干预措施,目标是解决在多种情绪障碍中常见的高度负面情绪、情绪反应性和情绪调节缺陷。我们的目标是收集关于UP-C疗效的初步随机对照试验(RCT)数据,将UP-C与一种积极的、以焦虑为重点的干预措施进行比较。参与者为47名患有至少一种原发性焦虑症的儿童;约一半有抑郁症状加重情况。参与者接受UP-C或焦虑重点控制治疗。在诊断缓解和焦虑症状方面未发现与治疗条件相关的差异。然而,在随访时的治疗反应、抑郁症状、悲伤调节障碍和认知重评方面观察到了有利于UP-C的差异。结果提供了初步证据,表明UP-C在治疗焦虑方面可能至少与得到充分支持的特定焦虑治疗方案一样有效,并且可能在某些情绪反应性和调节变量方面产生更大的改善。

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