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1998年至2011年间,美国胸腰椎脊柱损伤的发病率有所增加吗?

Has the incidence of thoracolumbar spine injuries increased in the United States from 1998 to 2011?

作者信息

Doud Andrea N, Weaver Ashley A, Talton Jennifer W, Barnard Ryan T, Meredith J Wayne, Stitzel Joel D, Miller Preston, Miller Anna N

机构信息

Department of General Surgery, Wake Forest School of Medicine, Winston-Salem, NC, USA.

出版信息

Clin Orthop Relat Res. 2015 Jan;473(1):297-304. doi: 10.1007/s11999-014-3870-9. Epub 2014 Aug 13.

Abstract

BACKGROUND

While most motor vehicle crash (MVC)-related injuries have been decreasing, one study showed increases in MVC-related spinal fractures from 1994 to 2002 in Wisconsin. To our knowledge, no studies evaluating nationwide trends of MVC-related thoracolumbar spine injuries have been published. Such fractures can cause pain, loss of functionality or even death. If the incidence of such injuries is increasing, it may provide a motive for reassessment of current vehicle safety design.

QUESTIONS/PURPOSES: We questioned whether the incidence of thoracolumbar spine injuries increased in the United States population with time (between 1998 and 2011), and if there was an increased incidence of thoracolumbar injuries, whether there were identifiable compensatory "trade-off injury" patterns, such as reductions in sacropelvic injuries.

PATIENTS AND METHODS

Institutional review board approval was obtained for retrospective review of three national databases: the National Trauma Databank® (NTDB®), 2002-2006, National Automotive Sampling System (NASS), 2000-2011, and National Inpatient Sample (NIS), 1998-2007. In each database, the total number of MVC-related injuries and the number of MVC-related thoracolumbar injuries per year were identified using appropriate Abbreviated Injury Scale (AIS) or ICD-9 codes. Sacropelvic injuries also were identified to evaluate their potential as trade-off injuries. Poisson regression models adjusting for age were used to analyze trends in the data with time.

RESULTS

All databases showed increases in MVC-related thoracolumbar spine injuries when adjusting for age with time. These age-adjusted relative annual percent increases ranged from 8.22% (95% CI, 5.77%-10.72%; p<0.001) using AIS of 2 or more (AIS2 +) injury codes in the NTDB®, 8.59% (95% CI, 5.88%-11.37%; p<0.001) using ICD-9 codes in the NTDB®, 8.12% (95% CI, 7.20%-9.06%; p<0.001) using ICD-9 codes in the NIS, and 8.10 % (95% CI 5.00%-11.28%; p<0.001) using AIS2+ injury codes in the NASS. As these thoracolumbar injuries have increased, there has been no consistent trend toward a compensatory reduction in terms of sacropelvic injuries.

CONCLUSIONS

While other studies have shown that rates of many MVC-related injuries are declining with time, our data show increases in the incidence of thoracolumbar injury. Although more sensitive screening tools likely have resulted in earlier and increased recognition of these injuries, it cannot be stated for certain that this is the only driver of the increased incidence observed in this study. As seatbelt use has continued to increase, this trend may be the result of thoracolumbar injuries as trade-offs for other injuries, although in our study we did not see a compensatory decrease in sacropelvic injuries. Investigation evaluating the root of this pattern is warranted.

摘要

背景

虽然大多数与机动车碰撞(MVC)相关的损伤一直在减少,但一项研究显示,1994年至2002年期间,威斯康星州与MVC相关的脊柱骨折有所增加。据我们所知,尚未有评估全国范围内与MVC相关的胸腰椎损伤趋势的研究发表。此类骨折可导致疼痛、功能丧失甚至死亡。如果此类损伤的发生率在增加,可能为重新评估当前车辆安全设计提供一个动机。

问题/目的:我们质疑美国人群中胸腰椎损伤的发生率是否随时间(1998年至2011年)增加,以及如果胸腰椎损伤的发生率增加,是否存在可识别的代偿性“权衡损伤”模式,例如骶骨盆损伤的减少。

患者和方法

获得机构审查委员会批准,对三个国家数据库进行回顾性研究:2002年至2006年的国家创伤数据库(NTDB®)、2000年至2011年的国家汽车抽样系统(NASS)以及1998年至2007年的国家住院患者样本(NIS)。在每个数据库中,使用适当的简明损伤定级(AIS)或国际疾病分类第九版(ICD - 9)编码确定每年与MVC相关的损伤总数以及与MVC相关的胸腰椎损伤数量。还确定了骶骨盆损伤,以评估其作为权衡损伤的可能性。使用针对年龄进行调整的泊松回归模型分析数据随时间的趋势。

结果

所有数据库在对年龄进行时间调整后均显示与MVC相关的胸腰椎损伤有所增加。这些经年龄调整的相对年增长率范围为:使用NTDB®中AIS为2级或更高(AIS2 +)损伤编码时为8.22%(95%置信区间,5.77% - 10.72%;p < 0.001),使用NTDB®中的ICD - 9编码时为8.59%(95%置信区间,5.88% - 11.37%;p < 0.001),使用NIS中的ICD - 9编码时为8.12%(95%置信区间,7.20% - 9.06%;p < 0.001),使用NASS中AIS2 +损伤编码时为8.10%(95%置信区间5.00% - 11.28%;p < 0.001)。随着这些胸腰椎损伤的增加,在骶骨盆损伤方面没有一致的代偿性减少趋势。

结论

虽然其他研究表明许多与MVC相关的损伤发生率随时间下降,但我们的数据显示胸腰椎损伤的发生率在增加。尽管更敏感的筛查工具可能导致对这些损伤的更早和更多识别,但不能确定这是本研究中观察到的发生率增加的唯一驱动因素。由于安全带的使用持续增加,这种趋势可能是胸腰椎损伤作为其他损伤的权衡结果,尽管在我们的研究中未看到骶骨盆损伤的代偿性减少。有必要对这种模式的根源进行调查。

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