埃及儿童中与致病性、集聚性和弥漫性黏附性大肠杆菌相关腹泻的流行病学和临床特征

The epidemiological and clinical characteristics of diarrhea associated with enteropathogenic, enteroaggregative and diffuse-adherent Escherichia coli in Egyptian children.

作者信息

Ahmed Salwa F, Shaheen Hind I, Abdel-Messih Ibrahim Adib, Mostafa Manal, Putnam Shannon D, Kamal Karim A, Sayed Abdel Nasser El, Frenck Robert W, Sanders John W, Klena John D, Wierzba Thomas F

机构信息

Research Science Directorate, US Naval Medical Research Unit No. 3, Cairo, Egypt

Research Science Directorate, US Naval Medical Research Unit No. 3, Cairo, Egypt.

出版信息

J Trop Pediatr. 2014 Oct;60(5):397-400. doi: 10.1093/tropej/fmu034. Epub 2014 Aug 13.

DOI:10.1093/tropej/fmu034

PMID:25122630

Abstract

A total of 220 enteroadherent Escherichia coli were identified from 729 Egyptian children with diarrhea using the HEp-2 adherence assay. Enteropathogenic E.coli (EPEC = 38) was common among children <6 months old and provoked vomiting, while diffuse-adhering E.coli (DAEC = 109) induced diarrheal episodes of short duration, and enteroaggregative E.coli (EAEC = 73) induced mild non-persistent diarrhea. These results suggest that EPEC is associated with infantile diarrhea in Egyptian children.

摘要

通过HEP-2黏附试验，从729名患腹泻的埃及儿童中总共鉴定出220株肠道黏附性大肠杆菌。致病性大肠杆菌（EPEC = 38）在6个月以下儿童中常见，并引发呕吐，而弥漫性黏附性大肠杆菌（DAEC = 109）导致短病程腹泻发作，肠集聚性大肠杆菌（EAEC = 73）导致轻度非持续性腹泻。这些结果表明，EPEC与埃及儿童的婴儿腹泻有关。