Lava Sebastiano A G, Bianchetti Mario G, Simonetti Giacomo D
Division of Pediatric Nephrology, University Children's Hospital Bern, Bern, Switzerland.
Pediatr Nephrol. 2015 Sep;30(9):1389-96. doi: 10.1007/s00467-014-2931-3. Epub 2014 Aug 17.
Sodium is the most abundant extracellular cation and therefore pivotal in determining fluid balance. At the beginning of life, a positive sodium balance is needed to grow. Newborns and preterm infants tend to lose sodium via their kidneys and therefore need adequate sodium intake. Among older children and adults, however, excessive salt intake leads to volume expansion and arterial hypertension. Children who are overweight, born preterm, or small for gestational age and African American children are at increased risk of developing high blood pressure due to a high salt intake because they are more likely to be salt sensitive. In the developed world, salt intake is generally above the recommended intake also among children. Although a positive sodium balance is needed for growth during the first year of life, in older children, a sodium-poor diet seems to have the same cardiovascular protective effects as among adults. This is relevant, since: (1) a blood pressure tracking phenomenon was recognized; (2) the development of taste preferences is important during childhood; and (3) salt intake is often associated with the consumption of sugar-sweetened beverages (predisposing children to weight gain).
钠是细胞外最丰富的阳离子,因此在决定体液平衡方面起着关键作用。在生命初期,需要正钠平衡来实现生长。新生儿和早产儿往往通过肾脏丢失钠,因此需要充足的钠摄入。然而,在大龄儿童和成年人中,过量的盐摄入会导致血容量增加和动脉高血压。超重、早产或小于胎龄儿以及非裔美国儿童因高盐摄入而患高血压的风险增加,因为他们更可能对盐敏感。在发达国家,儿童的盐摄入量通常也高于推荐摄入量。虽然在生命的第一年生长需要正钠平衡,但在大龄儿童中,低钠饮食似乎与成年人一样具有心血管保护作用。这很重要,因为:(1)认识到血压轨迹现象;(2)儿童期口味偏好的形成很重要;(3)盐的摄入往往与含糖饮料的消费相关(使儿童易患体重增加)。